Abstract

Essential oils are composed of volatile components, and rapidly evaporate. It is desirable to formulate them in a cover protecting the essential oils against environmental conditions. Applying nanotechnology to preparing desirable formulations of essential oils can be provided in a cover along with controlled release, increased oil life and greater mobility. In this study, nanoparticles were prepared using polycaprolactone and chitosan aimed at encapsulation of Rosmarinus officinalis and Zataria multiflora essential oils. The nanoparticles were characterized in terms of size, polydispersity, encapsulation efficiency, and scanning electron microscope photomicrographs. The nanoparticles showed a positive surface charge ranging between +11.60 and +29.20 mV and a mean particle radius ranging between 181-407 nm. Encapsulation efficiency was obtained between 75.8-84.4% under different preparation conditions. The LC₅₀ values of fumigant toxicity of R. officinalis essential oil and nanoparticles were equal to 103.53 and 112.64 μL/L air, and for Z. multiflora essential oil and nanoparticles, they were equal to 195.13 and 206.66 μL/L air, respectively for 24 h exposure time against Tribolium confusum. The effectiveness of non- formulated essential oils was significantly (P < 0.05) lower than nanoencapsulated oils in the confused flour beetle adults for a long period under the same condition, due to the sustained release of the essentials provided by the formulation.

摘要

精油由挥发性成分组成，并迅速蒸发。希望将它们配制在保护精油免受环境条件影响的覆盖物中。将纳米技术应用于制备理想的精油配方可以在封面中提供，同时控制释放、延长油的寿命和更大的流动性。在这项研究中，使用聚己内酯和壳聚糖制备纳米颗粒，旨在包封迷迭香和杂花香精油。纳米颗粒在尺寸、多分散性、封装效率和扫描电子显微镜照片方面进行了表征。纳米粒子显示出范围在 +11.60 和 +29.20 之间的正表面电荷 mV 和 181-407  nm 范围内的平均粒子半径。不同制备条件下的包封率在75.8-84.4%之间。R. officinalis精油和纳米粒子的熏蒸毒性LC ₅₀值分别等于 103.53 和 112.64 μL/L 空气，对于何首乌精油和纳米粒子，它们分别等于 195.13 和 206.66 μL/L 空气对Tribolium confusum的24小时暴露时间。非配方精油的有效性显着（P <     0.05) 由于配方提供的必需成分的持续释放，在相同条件下长时间在糊涂面粉甲虫成虫中低于纳米包封油。