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Enhanced in vitro antimicrobial activity of amphotericin B with berberine against dual‐species biofilms of Candida albicans and Staphylococcus aureus
Journal of Applied Microbiology ( IF 3.2 ) Pub Date : 2020-09-29 , DOI: 10.1111/jam.14872
Shanjun Gao 1 , Shoumin Zhang 2 , Shuzhen Zhang 1, 2
Affiliation  

Multi‐species biofilms formed by fungi and bacteria are clinically common and confer the commensal micro‐organisms with protection against antimicrobial therapies. Previously, the plant alkaloid berberine was reported to show antimicrobial efficacy to eliminate bacterial and fungal biofilms. In this study, the combination of berberine and amphotericin B, an antifungal agent, was evaluated against dual‐species Candida albicans/Staphylococcus aureus biofilms.

中文翻译:

小碱两性霉素B对白念珠菌和金黄色葡萄球菌双物种生物膜的体外抗菌活性增强

由真菌和细菌形成的多种生物膜在临床上很常见,并赋予普通微生物以抗微生物治疗的保护。以前,据报道植物生物碱小ber碱具有消除细菌和真菌生物膜的抗菌功效。在这项研究中,针对小白念珠菌/金黄色葡萄球菌生物膜对小ber碱和两性霉素B(一种抗真菌剂)的组合进行了评估。
更新日期:2020-09-29
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