SARS‐COV‐2 (COVID‐19): Cellular and biochemical properties and pharmacological insights into new therapeutic developments,CELL BIOCHEMISTRY AND FUNCTION

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SARS‐COV‐2 (COVID‐19): Cellular and biochemical properties and pharmacological insights into new therapeutic developments
CELL BIOCHEMISTRY AND FUNCTION ( IF 3.6 ) Pub Date : 2020-09-29 , DOI: 10.1002/cbf.3591
Hakan Parlakpinar ₁ , Mehmet Gunata ₁

Affiliation

COVID‐19 caused by SARS‐COV‐2 first appeared in the Wuhan City of China and began to spread rapidly among people. Rapid progression of the outbreak has led to a major global public health problem of a potentially fatal disease. On January 30, 2020, WHO declared the pandemic as the sixth public health emergency of the world. Upon this, the whole country has started to take the necessary precautions. The new coronavirus uses membrane‐bound angiotensin‐converting enzyme 2 (ACE2) to enter into the cells, such as SARS‐CoV, and mostly affects the respiratory tract. Symptoms of COVID‐19 patients include fever (93%), fatigue (70%), cough (70%), anorexia (40%) and dyspnoea (34.5%). The elderly and people with underlying chronic diseases are more susceptible to infection and higher mortality. Currently, a large number of drugs and vaccines studies are ongoing. In this review, we discussed the virology, epidemiological data, the replication of the virus, and its relationship with cardiovascular diseases on COVID‐19 pandemics, treatment and vaccines. Thereby, this study aims to neatly present scientific data in light of many regarding literature that can be a clue for readers who research this disease prevention and treatment.

更新日期：2020-09-29

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