Mostly, collagen is obtained from mammalian sources, but its use is limited because of high cost and various allergic reactions. In this review, different alternative sources of collagen were explored and methods for isolation and peptide generations are summarized. Bioactive peptides are short sequences of 2–20 amino acid residues with positive effect on human health. This review summarizes various biological activities of sea food derived peptides/hydrolysates includes antioxidant, inflammatory, antifreeze, angiotension-I converting enzyme (ACE-I) inhibition, antimicrobial, antiaging, wound healing and anticoagulant activities. Moreover, this review also highlights the therapeutic potential and importance of sea-food derived peptides in various pharmaceutical, biomedical, food and cosmetic industries. This review also proposes biological solution for utilization of seafood derived waste in the development of collagen-based food ingredients that is otherwise cause environmental pollution.

通常，胶原蛋白是从哺乳动物来源获得的，但由于成本高和各种过敏反应，其使用受到限制。在这篇综述中，探讨了胶原蛋白的不同替代来源，并总结了分离和产生肽的方法。生物活性肽是2-20个氨基酸残基的短序列，对人类健康有积极影响。这篇综述总结了海鲜衍生肽/水解产物的各种生物活性，包括抗氧化剂，炎症，抗冻剂，血管紧张素I转化酶（ACE-I）抑制，抗菌，抗衰老，伤口愈合和抗凝活性。此外，本综述还强调了海鲜衍生肽在各种制药，生物医学，食品和化妆品工业中的治疗潜力和重要性。