Sustainable agriculture requires the recruitment of bacterial agents to control diverse plant diseases such as bacterial endophytes. Bacterial endophytes colonize and inhabit internal plant tissues without causing any apparent damage. Within the plant, these bacteria exert multiple beneficiary effects, including direct stimulation of plant growth by the action of phytohormones or the production of metabolites. However, bacterial endophytes also protect their plant host through biocontrol pathogens or by inducing plant innate immune system. The present work makes a systematic and in-depth review on the current state of endophytic bacterial diversity, their plant colonization strategies, and their potential roles as protective agents against plant diseases during pre- and post-harvest stages of crop productivity. In addition, an exploration of their beneficial effects on sustainable agriculture by reducing/eliminating the use of toxic agrochemicals was conducted. Finally, we propose diverse effective strategies for the application of endophytic bacteria as biological agents during both pre- and post-harvest stages, with the aim of protecting crop plants and their agricultural products.

可持续农业需要招募细菌因子来控制多种植物病害，例如细菌内生菌。细菌内生菌定植并栖息在植物内部组织中，而不会造成任何明显的损害。在植物中，这些细菌发挥多种有益作用，包括通过植物激素的作用或代谢产物的产生直接刺激植物的生长。但是，细菌内生菌还可以通过生物控制病原体或诱导植物先天免疫系统来保护其植物宿主。本工作对内生细菌多样性的现状，它们的植物定植策略及其在作物生产前和收获后作为植物病害防护剂的潜在作用进行了系统，深入的综述。此外，通过减少/消除有毒农药的使用，探讨了它们对可持续农业的有益影响。最后，我们提出了在收获前和收获后阶段将内生细菌作为生物制剂应用的多种有效策略，旨在保护农作物及其农产品。