Mycotoxins represent substantial challenges to the farming industry. These include toxins produced by Fusarium fungi, particularly trichothecenes (toxin T-2) and fumonisin (FB₁). In the present study, we determined the effects of addition on Saccharomyces cerevisiae lysate (SCL) added to feed contaminated with T-2 and FB₁ in terms of health, productive efficiency, and egg laying quality. We used 60 Hy-line Brown laying hens, and divided them into five groups with four repetitions per group and three birds per repetition. There was one group with no contamination with toxin (NoC). The four other groups included combinations of mycotoxin (4 ppm T-2, and 20 ppm FB1): A contamination group was used as control (the C+ group), and another two contained 500 g/ton of SCL (Detoxa Plus®) (the C + D500 group) or 1000 g/ton of SCL (the C + D1000 group). Finally, one group received feed containing 500 g/ton of Detoxa Plus® and 1000 g/ton of Uniwall® MOS 25 (the C + D500 + U1000 group). The experimental period was 84 days, divided into three productive cycles of 28 days each. The NoC hens had greater egg production than the other groups. Hens that consumed feed with SCL had greater egg production than did the C+ group. The NoC hens produced eggs with greater weights than did the C hens; however, C + D1000 and C + D500 + U1000 birds produced greater egg weights than did the C+ group. The C+ group produced lower egg masses than did the NoC and C + D500 + U1000 groups. The feed intake (FI) was lower in hens that ingested mycotoxin. The use of SCL in feed minimized the negative effects of mycotoxin on feed conversion ratio (FI/dozen). Effects of treatment were detected for feed conversion ratio (kg/kg). The hens that consumed mycotoxin had lower shell resistance and thickness compared to those in the NoC group. The red color of egg yolk was greater in the control groups. There were fluctuations in levels of liver enzymes when birds consumed mycotoxin (sometimes reduced and sometimes increased); nevertheless, the cumulative effect increased the activity of alanine aminotransferase. The serum concentration of reactive oxygen species was greater in hens that ingested mycotoxin only on d 84 compared to the NoC group. Serum glutathione S-transferase activity was greater on d 56 in C + D500 and C + D1000 hens than in the others. We conclude that, in general, the consumption of mycotoxin impaired the performance and quality of the eggs of the hens; the addition of the S. cerevisiae lysate and the addition organic acids, yeast cell wall and mineral carrier minimized some of the negative effects caused by T-2 and FB1.

霉菌毒素是农业的重大挑战。这些包括镰刀菌真菌产生的毒素，尤其是毛孢菌毒素（毒素T-2）和伏马菌毒素（FB ₁）。在本研究中，我们确定了添加物对添加到受T-2和FB ₁污染的饲料中的酿酒酵母裂解物（SCL）的影响。在健康，生产效率和产蛋质量方面。我们使用了60头Hy-line Brown产蛋母鸡，将它们分为五组，每组四只，每组三只。一组没有毒素污染（NoC）。其他四个组包括霉菌毒素的组合（4 ppm T-2和20 ppm FB1）：污染组用作对照组（C +组），另外两个包含500 g /吨SCL（DetoxaPlus®）（ C + D500组）或1000克/吨SCL（C + D1000组）。最后，一组接受含500克/吨DetoxaPlus®和1000克/吨Uniwall®MOS 25的饲料（C + D500 + U1000组）。实验期为84天，分为三个生产周期，每个生产周期28天。NoC母鸡的产蛋量高于其他组。食用SCL饲料的母鸡的产蛋量高于C +组。NoC母鸡产生的蛋比Chen母鸡重。但是，C + D1000和C + D500 + U1000禽类产生的蛋重比C +组更大。与NoC组和C + D500 + U1000组相比，C +组产生的蛋量更低。摄入霉菌毒素的母鸡的采食量（FI）较低。在饲料中使用SCL可将霉菌毒素对饲料转化率（FI /十二）的负面影响降至最低。检测了饲料转化率（kg / kg）的处理效果。与NoC组相比，食用霉菌毒素的母鸡的壳抗性和厚度较低。对照组的蛋黄红色较大。当家禽食用霉菌毒素时，肝酶水平会有波动（有时会减少，有时会增加）；然而，累积作用增加了丙氨酸转氨酶的活性。与NoC组相比，仅在第84天摄入霉菌毒素的母鸡的活性氧种类的血清浓度更高。C + D500和C + D1000母鸡的第56天的血清谷胱甘肽S-转移酶活性高于其他几只。我们得出的结论是，一般而言，食用霉菌毒素会损害母鸡卵的性能和质量。的加法 C + D500和C + D1000母鸡中，第56天的血清谷胱甘肽S-转移酶活性高于其他人。我们得出的结论是，一般而言，食用霉菌毒素会损害母鸡卵的性能和质量。的加法 C + D500和C + D1000母鸡中，第56天的血清谷胱甘肽S-转移酶活性高于其他人。我们得出的结论是，一般而言，食用霉菌毒素会损害母鸡卵的性能和质量。的加法酿酒酵母裂解物和有机酸，酵母细胞壁和矿物质载体的添加将T-2和FB1引起的某些负面影响降至最低。