Medicinal plants are key components of the livelihoods of rural people, who rely on forest resources in the Nepal Himalaya, and this reliance is particularly high in hills and mountainous areas. Persistent premature and overharvesting, and inadequate knowledge of sustainable harvesting are additional threats to medicinal plants, acerbated by land use- and climate change. The data and knowledge regarding the current and potential future distribution of high value medicinal plants in Nepal is relatively sparse. We carried out predictive distribution and habitat modeling for Dactylorhiza hatagirea (D. Don) Soo, Paris polyphylla Sm. and Taxus species to understand their potential distribution, and to examine challenges affecting the natural habitat of these species, which are exposed to a rapidly changing physical and biological environment. The studied species are over-exploited, although conservation initiatives are in place in Nepal. Our predictions show that the potentially suitable habitats of these medicinal plants will expand northward, indicating that more suitable habitats will be available in the future, might be corroborated with climate change effects. We do believe that the findings of this study are highly instrumental for demarcating the future distribution range of high value medicinal plants, to pursue an effective and sustainable management. However, both distribution and habitats of medicinal plants will face a high risk of habitat loss in response to increasing human population, herbal demand and lack of knowledge of sustainable harvesting.

药用植物是农村人民生计的关键组成部分，他们依赖尼泊尔喜马拉雅山的森林资源，而这种依赖在丘陵和山区尤为严重。持久的过早和过度采收以及对可持续收割的了解不足，是对药用植物的又一威胁，这是由于土地利用和气候变化而造成的。有关尼泊尔高价值药用植物当前和潜在未来分布的数据和知识相对较少。我们进行了预测分布和栖息地建模Dactylorhiza hatagirea（D.唐）洙，七叶一枝花SM。和红豆杉物种以了解其潜在分布，并研究影响这些物种自然栖息地的挑战，因为这些物种面临着快速变化的物理和生物环境。尽管尼泊尔已经采取了保护措施，但已对物种进行了过度开发。我们的预测表明，这些药用植物的潜在适宜生境将向北扩展，这表明未来可能会有更多适宜生境，这可能与气候变化的影响相吻合。我们确实相信，这项研究的发现对于界定高价值药用植物的未来分布范围，追求有效和可持续的管理非常有帮助。然而，