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BnaSNPDB: An interactive web portal for the efficient retrieval and analysis of SNPs among 1,007 rapeseed accessions
Computational and Structural Biotechnology Journal ( IF 6 ) Pub Date : 2020-09-29 , DOI: 10.1016/j.csbj.2020.09.031
Tao Yan , Qian Wang , Antony Maodzeka , Dezhi Wu , Lixi Jiang

The rapid development of high-throughput sequencing technology and the decrease in sequencing costs provide valuable resources and great opportunities for researchers to investigate genomic variations across hundreds or even thousands of accessions in the post-genomic era. The management and exploration of these large-scale genomic variations heavily rely on programming and command-line environments, which are challenging and time-consuming for most experimental biologists and plant breeders. Here, we present BnaSNPDB, an interactive web portal with a user-friendly interface that provides multiple analysis modules for retrieving, analyzing, and visualizing single nucleotide polymorphisms among 1,007 accessions of worldwide rapeseed germplasm. It is compatible, extendable, and portable to be easily set up on different operating systems, and can be accessed at http://121.41.229.126:3838/bnasnpdb and http://rapeseed.zju.edu.cn:3838/bnasnpdb. Its whole dataset and code are available at https://github.com/YTLogos/BnaSNPDB. This database is essential for accelerating studies on the functional genomics and screening of the molecular markers of molecular-assisted breeding in rapeseed.



中文翻译:

BnaSNPDB:一个交互式的门户网站,可有效检索和分析1,007个油菜籽中的SNP

高通量测序技术的飞速发展和测序成本的降低为研究人员提供了宝贵的资源,并为研究人员研究后基因组时代跨越数百乃至数千种种质的基因组变异提供了巨大的机会。这些大规模基因组变异的管理和探索在很大程度上依赖于编程和命令行环境,这对大多数实验生物学家和植物育种者而言都是挑战且耗时的。在这里,我们介绍BnaSNPDB,这是一个具有用户友好界面的交互式Web门户,该门户提供了多个分析模块,用于检索,分析和可视化全球油菜籽种质的1,007个品种中的单核苷酸多态性。它具有兼容性,可扩展性和便携性,可以轻松地在不同的操作系统上进行设置,可以访问http://121.41.229.126:3838/bnasnpdb和http://rapeseed.zju.edu.cn:3838/bnasnpdb。其整个数据集和代码可在https://github.com/YTLogos/BnaSNPDB获得。该数据库对于加快功能基因组学的研究和油菜籽分子育种分子标记的筛选至关重要。

更新日期:2020-09-30
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