Abstract

Surface properties of aqueous dispersions of bovine serum albumin complexes with silica nanoparticles have been studied using a set of methods that are sensitive to changes in the structure and composition of surface layers. In spite of the similar charges of the components, their interaction leads to changes in the surface properties of the dispersions; namely, the rates of variations in the dynamic surface elasticity and dynamic surface tension decrease due to the high electrostatic barrier of adsorption. The addition of an electrolyte decreases the electrostatic barrier. In this case, the adsorption of the complexes leads to a growth in the dynamic surface elasticity from the values characteristic of pure bovine serum albumin solutions (~80 mN/m) to 170 mN/m, which corresponds to the formation of macroscopically homogeneous adsorption film of nanoparticle–protein complexes.

中文翻译：

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牛血清白蛋白复合物与二氧化硅纳米粒子溶液的动态表面性质

摘要

牛血清白蛋白复合物与二氧化硅纳米粒子的水分散体的表面性质已使用一套对表面层的结构和组成变化敏感的方法进行了研究。尽管各组分的电荷相似，但它们的相互作用导致分散体的表面性质发生变化。即，由于高的静电吸附壁垒，动态表面弹性和动态表面张力的变化率降低。电解质的添加降低了静电屏障。在这种情况下，配合物的吸附会导致动态表面弹性从纯牛血清白蛋白溶液的特征值（约80 mN / m）增加到170 mN / m，