Clinical presentation and outcomes of SARS-CoV-2 related encephalitis: the ENCOVID multicentre study,The Journal of Infectious Diseases

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Clinical presentation and outcomes of SARS-CoV-2 related encephalitis: the ENCOVID multicentre study
The Journal of Infectious Diseases ( IF 5.0 ) Pub Date : 2020-09-28 , DOI: 10.1093/infdis/jiaa609
Andrea Pilotto _{1,

2} , Stefano Masciocchi ₁ , Irene Volonghi ₁ , Massimo Crabbio ₃ , Eugenio Magni ₃ , Valeria De Giuli ₄ , Francesca Caprioli ₄ , Nicola Rifino ₅ , Maria Sessa ₅ , Michele Gennuso ₆ , Maria Sofia Cotelli ₇ , Marinella Turla ₇ , Ubaldo Balducci ₈ , Sara Mariotto ₉ , Sergio Ferrari ₉ , Alfonso Ciccone ₁₀ , Fabrizio Fiacco ₁₁ , Alberto Imarisio ₁ , Barbara Risi ₁ , Alberto Benussi ₁ , Enrico Premi ₁₂ , Emanuele Focà ₁₃ , Francesca Caccuri ₁₄ , Matilde Leonardi ₁₅ , Roberto Gasparotti ₁₆ , Francesco Castelli ₁₃ , Gianluigi Zanusso ₉ , Alessandro Pezzini ₁ , Alessandro Padovani ₁ ,

Affiliation

Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Italy
Parkinson’s Disease Rehabilitation Centre, FERB ONLUS – S. Isidoro Hospital, Trescore Balneario (BG), Italy
Neurology Unit, Poliambulanza Hospital, Brescia, Italy
Neurology Unit, Istituti Ospedalieri, ASST Cremona, Cremona, Italy
Department of Neurology, Papa Giovanni XXIII Hospital, ASST Papa Giovanni XXII, Bergamo, Italy
Neurology Unit, Crema Hospital, Crema, Italy
Neurology Unit, ASST Valcamonica, Esine, Brescia, Italy
Neurology Unit, ASST Chiari, Chiari, Italy
Neurology Unit, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy
Department of Neurology and Stroke Unit, Carlo Poma Hospital, ASST Mantova, Mantova, Italy
Neurology Unit, ASST Bergamo Est, Seriate, Italy
Stroke Unit, ASST Spedali Civili di Brescia, Italy
University Division of Infectious and Tropical Diseases, University of Brescia and ASST Spedali Civili Hospital, Brescia, Italy
Microbiology Unit, Department of Molecular and Translational Medicine, University of Brescia and ASST Spedali Civili Hospital, Brescia, Italy
Neurology, Public Health, Disability Unit - IRCCS Neurology Institute Besta, Milan, Italy
Neuroradiology Unit, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia and ASST Spedali Civili Hospital, Brescia, Italy

Several preclinical and clinical investigations have argued for nervous system involvement in SARS-CoV-2 infection. Some sparse case reports have described various forms of encephalitis in COVID-19 disease, but very few data have focused on clinical presentations, clinical course, response to treatment and outcomes.

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