Abstract Cyclic-di-GMP (c-di-GMP) is a ubiquitous bacterial second messenger which has been associated with a motile to sessile lifestyle switch in many bacteria. Here, we review recent insights into c-di-GMP regulated processes related to environmental adaptations in alphaproteobacterial rhizobia, which are diazotrophic bacteria capable of fixing nitrogen in symbiosis with their leguminous host plants. The review centers on Sinorhizobium meliloti, which in the recent years was intensively studied for its c-di-GMP regulatory network.

中文翻译：

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控制α-变形菌根瘤菌自由生活的循环di-GMP信号

摘要 Cyclic-di-GMP (c-di-GMP) 是一种普遍存在的细菌第二信使，在许多细菌中与能动到固着的生活方式转换有关。在这里，我们回顾了最近对与 alphaproteobacterial 根瘤菌中环境适应相关的 c-di-GMP 调节过程的见解，这些根瘤菌是能够与其豆科宿主植物共生固氮的固氮细菌。审查集中在苜蓿中华根瘤菌上，近年来对其 c-di-GMP 监管网络进行了深入研究。