This is a 38‐year‐old married registered nurse diagnosed with ultra‐rapid cycling bipolar disorder presenting with an unusual picture of primarily manic/hypomanic episodes (at a ratio of approximately 10:1) vs. depressive episodes. The patient’s illness started at age 19 and was marked by psychotic mania along with classic manic symptoms. Resisting formal treatment for some 3 years, a primary treatment was attempted with a series of antidepressants and antipsychotics including citalopram and haloperidol with marginal tolerability and success. She was later stabilized on lithium but became nonadherent and went on to treatment with lamotrigine, which resulted in the development of Stevens‐Johnson syndrome.

中文翻译：

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来曲唑诱发躁狂症一例

这是一名38岁的已婚注册护士，被诊断患有超快速自行车双相情感障碍，表现出以躁狂/低躁狂发作（约10：1的比率）与抑郁发作的不同寻常的画面。患者的疾病始于19岁，主要表现为精神病性躁狂症和典型的躁狂症状。抵抗正式治疗约3年，尝试用一系列抗抑郁药和抗精神病药（包括西酞普兰和氟哌啶醇）进行初步治疗，但其耐受性和成功率均较低。后来她靠锂稳定下来，但失去了依从性，继续接受拉莫三嗪治疗，这导致了史蒂文斯-约翰逊综合征的发展。