The azido group is found in large numbers of natural products, drugs, biochemicals and materials and to date,many elegant and useful methods for the synthesis of organic azides and their transformations have been documented. In this review, we provide a summary of the state of the art of radical azidation for the construction of C(sp3)-N3 bonds. There is a specific emphasis on the synthetic reactions involving C(sp3)-H azidation, decar-boxylative azidation and difunctionalized azidation of olefins. This review will be useful to those working in this field and hopefully could inspire further development of radical azidation reactions.

中文翻译：

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自由基叠氮化作为构建C（sp3）-N 3键的手段

叠氮基团存在于大量的天然产物，药物，生化试剂和材料中，迄今为止，已有许多优雅而有用的方法用于合成有机叠氮化物及其转化。在这篇综述中，我们提供了用于C（sp3）-N3键的自由基叠氮化的最新技术概述。特别强调涉及烯烃的C（sp3）-H叠氮化，十烷基化叠氮化和双官能叠氮化的合成反应。这篇综述对在该领域工作的人们将是有用的，并希望可以激发激进的叠氮化反应的进一步发展。