Paraneoplastic cerebellar degeneration associated with anti-protein kinase Cgamma antibodies in a Chinese patient,Journal of Neuroimmunology

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Paraneoplastic cerebellar degeneration associated with anti-protein kinase Cgamma antibodies in a Chinese patient
Journal of Neuroimmunology ( IF 2.9 ) Pub Date : 2021-01-01 , DOI: 10.1016/j.jneuroim.2020.577408
Haitao Ren ₁ , Dachun Zhao ₂ , Xiaolu Xu ₁ , Yingmai Yang ₁ , Siyuan Fan ₁ , Wenhan Li ₃ , Hongzhi Guan ₁

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Anti-protein kinase Cgamma (anti-PKCγ) antibodies are rare onconeural antibodies associated with paraneoplastic cerebellar degeneration (PCD). To date, only two patients with PCD and anti-PKCγ antibodies have been reported. Here, we report a Chinese patient with PCD and anti-PKCγ antibodies. Screening for tumor revealed lymphoepithelial carcinoma in tonsil. The patient's symptoms improved gradually after radiotherapy for the lymphoepithelial carcinoma and intravenous immunoglobulin immunotherapy.

更新日期：2021-01-01

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