Congenital ventricular diverticulum is a rare anomaly with an unclear pathology. Here, we report a male fetus at 24 weeks of gestation, diagnosed with right ventricular diverticulum associated with tetralogy of Fallot and absent pulmonary valve. The diverticulum was located at the anterosuperior wall of the right ventricle and faced into the massive pulmonary regurgitation flow jet. Intrauterine fetal death from heart failure resulted at 26 weeks of gestation. An autopsy revealed significant subendocardial fibrosis in the diverticular wall without inflammatory cell infiltration. Clinical and pathologic features suggested that the regurgitative blood flow contributed to the formation of the right ventricular diverticulum.

先天性室性憩室是一种罕见的异常，病理尚不清楚。在这里，我们报告了一个在妊娠24周时被诊断为右室憩室并伴有法洛四联症和肺动脉瓣缺失的男性胎儿。憩室位于右心室前上壁，面对大量的肺返流射流。妊娠26周时因心力衰竭导致宫内胎儿死亡。尸检显示在憩室壁有明显的心内膜下纤维化，而没有炎性细胞浸润。临床和病理学特征提示反流血流有助于右心室憩室的形成。