Here we present an anti-CD3 loaded PLGA/ALG/CHI Mg micromotor systems, with degradable constituents and Mg-water reaction propulsion, thus ensuring a superior biocompatibility. Porous hydrogel formed by ALG/CHI offers high capacity of antigen loading, along with biocompatibility. By efficient loading of anti-human CD3 as an antigen and activating the calcium ion channel of Jurkat T cell, vital for immunotherapy, the motor system extends the application scope of micro/nanomotor systems from cargo (drug) delivery to interaction with the biointerface and immune activity modulation.

中文翻译：

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水动力和抗CD3负载mg微电机用于T细胞活化

在这里，我们介绍了一种抗CD3负载的PLGA / ALG / CHI Mg微电机系统，具有可降解的成分和Mg-水反应推进作用，从而确保了优异的生物相容性。由ALG / CHI形成的多孔水凝胶具有很高的抗原负载能力以及生物相容性。通过有效加载抗人CD3作为抗原，并激活Jurkat T细胞的钙离子通道（对免疫疗法至关重要），该运动系统将微/纳米运动系统的应用范围从货物（药物）输送扩展到了与生物界面的相互作用。免疫活性调节。