Hyperthermia is used to destroy tumors by generating heat in the body (40–45 °C). In particular, regional hyperthermia entails intense heating of tumors rather than raising the temperature of the body. In regional hyperthermia, the prediction of the tumor temperature before treatment is essential to ensure treatment efficiency and patient safety. The goal of this study is to predict the temperature of tumors in regional hyperthermia by using a light emitting diode (LED). LED luminance shows a linear relationship with current above a certain voltage. Thus, the temperature may be predicted via LED luminance based on these electrical characteristics, Special Absorption Rate (SAR), and Pennes’ Bio-heat Transfer Equation. LED was located in the agar phantom at the same intervals to measure the luminance, and measure temperature at same spot using thermometer and well verified using a commercialized simulation program (Sim4Life). Within the range of electrode size, the difference in luminance between the predicted and the measured temperatures was within 2.5%. In addition, the difference between the predicted temperature and the result of the simulation program was within 1.5%. In this study, the tumor temperature in regional hyperthermia was predicted using LED luminance to ensure treatment accuracy and patient safety. This study showed the possibility of temperature prediction based on LED luminance.

中文翻译：

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利用LED亮度预测局部热疗中的肿瘤温度

热疗用于通过在体内产生热量 (40–45 °C) 来破坏肿瘤。特别是，局部热疗需要对肿瘤进行强烈加热，而不是升高身体的温度。在局部热疗中，治疗前预测肿瘤温度对于确保治疗效率和患者安全至关重要。本研究的目的是通过使用发光二极管 (LED) 来预测局部热疗中肿瘤的温度。LED 亮度在一定电压以上与电流呈线性关系。因此，可以基于这些电气特性、特殊吸收率 (SAR) 和 Pennes 的生物热传递方程，通过 LED 亮度来预测温度。LED 以相同的间隔位于琼脂模型中以测量亮度，并使用温度计测量同一地点的温度，并使用商业化的模拟程序 (Sim4Life) 进行充分验证。在电极尺寸范围内，预测温度与实测温度之间的亮度差异在2.5%以内。此外，预测温度与模拟程序结果之间的差异在 1.5% 以内。在这项研究中，使用 LED 亮度预测局部热疗中的肿瘤温度，以确保治疗准确性和患者安全。该研究显示了基于 LED 亮度进行温度预测的可能性。预测温度与模拟程序结果之间的差异在 1.5% 以内。在这项研究中，使用 LED 亮度预测局部热疗中的肿瘤温度，以确保治疗准确性和患者安全。该研究显示了基于 LED 亮度进行温度预测的可能性。预测温度与模拟程序结果之间的差异在 1.5% 以内。在这项研究中，使用 LED 亮度预测局部热疗中的肿瘤温度，以确保治疗准确性和患者安全。该研究显示了基于 LED 亮度进行温度预测的可能性。