Structural organization of the microcirculatory bed and mast cells in the uterus of mature female Wistar rats (n=60) were examined every 2 h over 24 h. During night hours, many vessels characterized by intensive reaction to NADPH-diaphorase and endothelial NO synthase were detected in the endometrium, and the density of these vessels and mast cells was quite high. During the day and evening hours, the capillaries with high levels of enzymes involved in NO synthesis and mast cells were less numerous. NO directly regulating the diameter of arteries and the intensity of transcapillary exchange can act as a signal molecule in the temporal dynamics of the vasoceptive action of estrogens and their receptors in the uterus.

中文翻译：

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不同时期大鼠子宫微循环床和肥大细胞组织动态

在 24 小时内每 2 小时检查一次成熟雌性 Wistar 大鼠（n = 60）子宫中微循环床和肥大细胞的结构组织。在夜间，在子宫内膜中检测到许多以对NADPH-心肌黄酶和内皮NO合酶反应强烈为特征的血管，这些血管和肥大细胞的密度相当高。在白天和晚上，参与一氧化氮合成和肥大细胞的酶含量高的毛细血管数量较少。NO直接调节动脉直径和经毛细血管交换的强度，可以作为雌激素及其受体在子宫内的血管感受作用的时间动态中的信号分子。