A new scordidesin А (1) and 2 known furo-clerodane diterpenoids, teucrin A (2) and 6-ketoteuscordin (3), were isolated by the phytochemical investigation of the acetone extract from the aerial parts of Teucrium scordium L. subsp. scordioides (Lamiaceae). The structure and stereochemistry of the compounds were established by high-resolution electrospray ionization mass spectrometry, infrared spectroscopy, and various ¹H nuclear magnetic resonance (NMR) and 2-dimensional-NMR techniques. Additionally, we report ¹³C NMR spectral data of 3 that were not published before. Antimicrobial activity of the compounds was tested against Gram-positive and Gram-negative bacteria belonging to 5 different species and against 2 strains of yeast belonging to 2 different species of the genus Candida.

通过对植物Te皮the属植物亚种的空中提取物的丙酮提取物进行植物化学研究，分离出一种新的scordidesinА（1）和2种已知的呋喃环烷二萜类化合物teucrin A（2）和6-ketoteuscordin（3）。scordioides（唇形科）。通过高分辨率电喷雾电离质谱，红外光谱以及各种¹ H核磁共振（NMR）和二维NMR技术确定了化合物的结构和立体化学。此外，我们报告了3的¹³ C NMR光谱数据以前没有发表过的。测试了该化合物对属于5个不同物种的革兰氏阳性和革兰氏阴性细菌以及针对属于假丝酵母属2个不同物种的2种酵母菌株的抗微生物活性。