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Differential mRNA and Long Noncoding RNA Expression Profiles in Umbilical Cord Blood Exosomes from Gestational Diabetes Mellitus Patients
DNA and Cell Biology ( IF 3.1 ) Pub Date : 2020-11-04 , DOI: 10.1089/dna.2020.5783
Minkai Cao 1 , Le Zhang 2, 3 , Yu Lin 4 , Zhengying Li 2 , Jianjuan Xu 1 , Zhonghua Shi 4 , Zhong Chen 1 , Jinqi Ma 5 , Juan Wen 3
Affiliation  

Background and Aims: Exosomes contain numerous RNAs and transfer them between cells or organs, thereby establishing intercellular or interorgan communication. The roles of mRNAs and long noncoding RNAs (lncRNAs) from umbilical cord blood exosomes in gestational diabetes mellitus (GDM) occurrence and fetus growth remain poorly understood. We aimed to establish the differential mRNA and lncRNA expression profiles in umbilical cord blood exosomes from GDM patients compared with normal controls.

中文翻译:

妊娠糖尿病患者脐带血外泌体的差异mRNA和长非编码RNA表达谱

背景和目的:外泌体包含许多RNA,并在细胞或器官之间转移它们,从而建立细胞间或器官间的通讯。脐血外泌体的mRNA和长非编码RNA(lncRNA)在妊娠糖尿病(GDM)发生和胎儿生长中的作用仍然知之甚少。我们旨在建立与正常对照相比,GDM患者脐带血外泌体中差异mRNA和lncRNA表达谱。
更新日期:2020-11-06
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