The ADGRL3 receptor, a member of the adhesion G-protein-coupled receptor family, is implicated in many neurological diseases. Using a novel technique involving controlled proteolysis of the receptor’s extracellular domain, this study demonstrated that ADGRL3 signals via G12/13 G proteins.

中文翻译：

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设计师粘附 GPCR 讲述其信号故事

ADGRL3 受体是粘附 G 蛋白偶联受体家族的成员，与许多神经系统疾病有关。这项研究使用一种涉及受体胞外域受控蛋白水解的新技术，证明 ADGRL3 通过 G12/13 G 蛋白发出信号。