Treatment failure in eosinophilic esophagitis (EoE) is common. We hypothesize that DNA methylation differs between patients by treatment response to topical steroids (oral viscous budesonide), thus offering the potential to inform targeting therapies.

中文翻译：

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嗜酸性粒细胞性食管炎的表观遗传甲基化：分子衰老和治疗反应的新生物标志物

嗜酸性粒细胞性食管炎 (EoE) 的治疗失败很常见。我们假设 DNA 甲基化因患者对局部类固醇（口服粘性布地奈德）的治疗反应而异，从而为靶向治疗提供了可能。