Abstract

The possibility of using microchannel flow reactors to obtain the kinetic and technological parameters of the synthesis of 1-butyl-3-methylimidazolium chloride (BMIMCl) ionic liquid is demonstrated for the reaction of 1-methylimidazole (MIm) with 1-chlorobutane with no solvents. BMIMCl is produced with high selectivity and specific output in a microchannel flow reactor at temperatures of 120–180°C a contact time of 2–45 min, and a pressure of 20 bar. A positive result is obtained, due to the laminar profile of the flow and a uniform distribution of the reagents concentration over the microchannel cross section. Studying the kinetics of the process in a microchannel flow reactor reveals a shift of the reaction to the mode of diffusive inhibition at temperatures above 150°C. The kinetic data obtained for BMIMCl synthesis are used to develop ways of producing 1-ethyl-3-methylimidazolium and 1-hexyl-3-methylimidazolium chlorides (EMIMCl and HMIMCl, respectively) under the conditions of a microchannel flow reactor. The approach proposed in this work is of interest in developing flow and periodic facilities for the low-tonnage production of dialkylimidazolium, ammonium, and pyridinium salts via quaternization of the corresponding alkyl chlorides and nitrogen-containing bases.

中文翻译：

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使用微通道反应器优化1-烷基-3-甲基咪唑鎓氯化物的生产

摘要

对于没有溶剂的1-甲基咪唑（MIm）与1-氯丁烷的反应，证明了使用微通道流动反应器获得合成1-丁基-3-甲基咪唑氯化物（BMIMCl）离子液体的动力学和工艺参数的可能性。 。BMIMCl是在微通道流动反应器中，温度为120–180°C，接触时间为2–45分钟，压力为20 bar的条件下以高选择性和比输出率生产的。由于流动的层状分布以及试剂浓度在微通道横截面上的均匀分布，因此获得了积极的结果。在微通道流动反应器中研究该过程的动力学发现，在高于150°C的温度下，反应向扩散抑制模式转移。用于BMIMCl合成的动力学数据用于开发在微通道流动反应器的条件下生产1-乙基-3-甲基咪唑鎓盐和1-己基-3-甲基咪唑鎓氯化物（分别为EMIMC1和HMIMCl）的方法。这项工作中提出的方法对于开发用于通过相应的烷基氯化物和含氮碱的季铵化低吨位生产二烷基咪唑鎓盐，铵盐和吡啶鎓盐的流程和定期设施非常有用。