The COVID‐19 pandemic has triggered numerous scientific activities aimed at understanding the SARS‐CoV‐2 virus and ultimately developing treatments. Structural biologists have already determined hundreds of experimental X‐ray, cryo‐EM, and NMR structures of proteins and nucleic acids related to this coronavirus, and this number is still growing. To help biomedical researchers, who may not necessarily be experts in structural biology, navigate through the flood of structural models, we have created an online resource, covid19.bioreproducibility.org, that aggregates expert‐verified information about SARS‐CoV‐2‐related macromolecular models. In this article, we describe this web resource along with the suite of tools and methodologies used for assessing the structures presented therein.

中文翻译：

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Covid-19.bioreproducibility.org：SARS-CoV-2 相关结构模型的网络资源


COVID-19 大流行引发了许多旨在了解 SARS-CoV-2 病毒并最终开发治疗方法的科学活动。结构生物学家已经确定了数百个与这种冠状病毒相关的蛋白质和核酸的实验 X 射线、冷冻电镜和核磁共振结构，而且这个数字仍在增长。为了帮助不一定是结构生物学专家的生物医学研究人员浏览大量的结构模型，我们创建了一个在线资源covid19.bioreproducibility.org ，该资源汇总了经过专家验证的有关 SARS-CoV-2 相关信息高分子模型。在本文中，我们描述了该网络资源以及用于评估其中呈现的结构的工具和方法套件。