A comparison of measurement properties between UK SF-6D and English EQ-5D-5L and Thai EQ-5D-5L value sets in general Thai population,Expert Review of Pharmacoeconomics & Outcomes Research

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A comparison of measurement properties between UK SF-6D and English EQ-5D-5L and Thai EQ-5D-5L value sets in general Thai population
Expert Review of Pharmacoeconomics & Outcomes Research ( IF 1.8 ) Pub Date : 2020-11-02 , DOI: 10.1080/14737167.2021.1829479
Krittaphas Kangwanrattanakul ₁

Affiliation

ABSTRACT

Background

Evidence is limited for comparative psychometric properties between EQ-5D-5L and SF-6D. Therefore, this study compared psychometric properties between those instruments using value sets from Thailand, England, and the UK in the general Thai population.

Methods

A total of 1,200 participants were recruited. The agreement level was evaluated using intraclass correlation coefficients (ICCs) and Bland–Altman plots. Convergent validity with SF-12v2 was assessed by Spearman’s rho correlations. Known-group validity compared discriminant activity and sensitivity between groups. Responsiveness was assessed using standardized effect sizes (SES) and standardized response mean (SRM).

Results

Agreement between SF-6D and Thai (ICCs = 0.51) and English (ICCs = 0.52) EQ-5D-5L index scores was good. The physical functioning demonstrated moderate to strong and moderate correlations with Thai (r = 0.50) and English (r = 0.46) EQ-5D-5L index scores, whereas SF-6D index scores strongly correlated with role emotion (r = 0.81). EQ-5D-5L was better than SF-6D at discrimination and sensitivity for gender, age, education level, household income, and number of diseases. The SF-6D was more responsive than the EQ-5D-5L for the worsened group.

Conclusion

Both SF-6D and EQ-5D-5L are valid among the general Thai population. Further studies should reinvestigate responsiveness and determine their impacts on economic analyses among patient groups.

中文翻译：

英国 SF-6D 和英国 EQ-5D-5L 和泰国 EQ-5D-5L 值集在泰国普通人群中的测量特性比较

摘要

背景

EQ-5D-5L 和 SF-6D 之间的比较心理测量学特性的证据有限。因此，本研究使用来自泰国、英国和英国的一般泰国人群的价值集比较了这些工具之间的心理测量特性。

方法

共招募了 1,200 名参与者。使用组内相关系数 (ICC) 和 Bland-Altman 图评估一致性水平。通过 Spearman 的 rho 相关性评估与 SF-12v2 的收敛有效性。已知组效度比较了组间的判别活性和敏感性。使用标准化效应大小 (SES) 和标准化响应平均值 (SRM) 评估响应性。

结果

SF-6D 与泰语 (ICCs = 0.51) 和英语 (ICCs = 0.52) EQ-5D-5L 指数得分一致。身体机能与泰语 (r = 0.50) 和英语 (r = 0.46) EQ-5D-5L 指数得分呈中度至强和中度相关，而 SF-6D 指数得分与角色情绪密切相关 (r = 0.81)。EQ-5D-5L在性别、年龄、教育程度、家庭收入、疾病数量等方面的辨别力和敏感性均优于SF-6D。对于恶化组，SF-6D 比 EQ-5D-5L 更敏感。