Human and plant pathogenic fungi have a major impact on public health and agriculture. Although these fungi infect very diverse hosts and are often highly adapted to specific host niches, they share surprisingly similar mechanisms that mediate immune evasion, modulation of distinct host targets and exploitation of host nutrients, highlighting that successful strategies have evolved independently among diverse fungal pathogens. These attributes are facilitated by an arsenal of fungal factors. However, not a single molecule, but rather the combined effects of several factors enable these pathogens to establish infection. In this review, we discuss the principles of human and plant fungal pathogenicity mechanisms and discuss recent discoveries made in this field.

中文翻译：

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感染过程中参与宿主免疫逃避、调节和利用的真菌因素

人类和植物病原真菌对公共卫生和农业有重大影响。尽管这些真菌感染非常多样化的宿主并且通常高度适应特定的宿主生态位，但它们在介导免疫逃避、不同宿主目标的调节和宿主营养物质的利用方面有着惊人的相似机制，这表明成功的策略已经在不同的真菌病原体之间独立进化。一系列真菌因素促进了这些属性。然而，不是单个分子，而是多个因素的综合作用使这些病原体能够建立感染。在这篇综述中，我们讨论了人类和植物真菌致病机制的原理，并讨论了该领域的最新发现。