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Time to recovery and predictors of severe community-acquired pneumonia among pediatric patients in Debre Markos referral hospital, North West Ethiopia: A retrospective follow-up study
PLOS ONE ( IF 2.9 ) Pub Date : 2020-09-25 , DOI: 10.1371/journal.pone.0239655
Belayneh Mengist , Mulugeta Tesfa , Bekalu Kassie

Introduction

Globally, pneumonia is a major cause of morbidity and mortality among children which leads to over 156 million episodes and 14.9 million hospitalizations each year. Besides this fact, the recovery time and predictors of children’s hospitalization related to severe community-acquired pneumonia is not well known. Therefore, the aim of this study was to estimate the median time to recovery and its predictors among severe community-acquired pneumonia patients admitted to the pediatric ward, Debre Markos referral hospital, North West Ethiopia.

Methods

An institution-based retrospective follow-up study was employed among 352 records of children who were admitted starting from January 2016 to December 2018. Patients' charts were retrieved using a structured data extraction tool. Cox proportional hazard model assumption and model fitness was checked. Stratified Cox regression was fitted as a final model. Hazard ratio with its 95% confidence interval was used and P-value < 0.05 was considered as a statistically significant association.

Result

The overall median recovery time was 4 days IQR (3–7). Recovery rate from severe community acquired pneumonia was 16.25 (95% CI: 14.54–18.15) per 100 person day observation. Age (AHR; 0.94 95% CI (0.90–0.98)), being stunted (AHR; 0.62 95% CI (0.43–0.91)), presence of danger sign at admission (AHR; 0.61 95% CI (0.40–0.94)), late presentation to seek care(AHR; 0.64 95% CI (0.47–0.88)) and co-morbidity (AHR; 0.45 95% CI (0.35–0.58)) were significant predictors of recovery time.

Conclusion

The median recovery time from severe community-acquired pneumonia was long so that measures to reduce recovery time should be strengthened.



中文翻译:

埃塞俄比亚西北部Debre Markos转诊医院的儿科患者恢复时间和严重社区获得性肺炎的预测指标:一项回顾性随访研究

介绍

在全球范围内,肺炎是儿童发病和死亡的主要原因,每年导致超过1.56亿次发作和1490万例住院治疗。除了这一事实,还不清楚重症社区获得性肺炎与儿童住院的恢复时间和预测因素有关。因此,本研究的目的是评估埃塞俄比亚西北部Debre Markos转诊医院儿科病房的重症社区获得性肺炎患者的中位恢复时间及其预测因素。

方法

从2016年1月至2018年12月,对352例入院儿童的记录进行了一项基于机构的回顾性随访研究。使用结构化数据提取工具检索患者的病历。考克斯比例风险模型假设和模型适用性进行了检查。分层Cox回归拟合为最终模型。使用具有95%置信区间的危险比,P值<0.05被认为具有统计学意义。

结果

总体中位恢复时间为4天IQR(3-7)。每100人日观察到的严重社区获得性肺炎的恢复率为16.25(95%CI:14.54-18.15)。年龄(AHR; 0.94 95%CI(0.90–0.98)),发育不良(AHR; 0.62 95%CI(0.43-0.91)),入院时有危险征象(AHR; 0.61 95%CI(0.40–0.94)) ,延迟就诊(AHR; 0.64 95%CI(0.47–0.88))和合并症(AHR; 0.45 95%CI(0.35-0.58))是恢复时间的重要预测指标。

结论

重度社区获得性肺炎的中位恢复时间较长,因此应加强减少恢复时间的措施。

更新日期:2020-09-25
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