The simulation of individual particle tracks and the chemical stage following water radiolysis in biological tissue is an effective means of improving our knowledge of the physico‐chemical contribution to the biological effect of ionizing radiation. However, the step‐by‐step simulation of the reaction kinetics of radiolytic species is the most time‐consuming task in Monte Carlo track‐structure simulations, with long simulation times that are an impediment to research. In this work, we present the implementation of the independent reaction times (IRT) method in Geant4‐DNA Monte Carlo toolkit to improve the computational efficiency of calculating G‐values, defined as the number of chemical species created or lost per 100 eV of deposited energy.

中文翻译：

---

Geant4-DNA 中的独立反应时间方法：实施和性能

生物组织中水辐射分解后的单个粒子轨迹和化学阶段的模拟是提高我们对电离辐射生物效应的物理化学贡献的认识的有效手段。然而，辐射分解物种反应动力学的逐步模拟是蒙特卡罗轨道结构模拟中最耗时的任务，模拟时间长是研究的障碍。在这项工作中，我们介绍了 Geant4-DNA Monte Carlo 工具包中独立反应时间 (IRT) 方法的实施，以提高计算 G 值的计算效率，G 值定义为每 100 eV 沉积物产生或丢失的化学物质数量。活力。