Background: Enhydra fluctuans Lour, a tropical herb, commonly known as helencha or harkuch, belongs to the family Asteraceae. It is an edible semi-aquatic herbaceous vegetable plant with serrate leaves and grows commonly in different parts of the world. Enhydra fluctuans possesses potential pharmacological role against inflammation, cancer, diarrhea, microbial infection, diabetes, etc.

Aim: This review aims to provide the most current information on the botanical characterization, distribution, traditional uses, chemical constituents, as well as the pharmacological activities of Enhydra fluctuans Lour.

Materials and Methods: The recently updated information on Enhydra fluctuans was gathered from scientific journals, books, and worldwide accepted scientific databases via a library and electronic search PubMed, Elsevier, Google Scholar, Springer, Scopus, Web of Science, Wiley online library. All of the full-text articles and abstracts related to Enhydra were screened. The most important and relevant articles were carefully chosen for study in this review.

Results: Crude extracts and isolated compounds of Enhydra fluctuans Lour have been reported to be pharmacologically active against cytoprotective, analgesic and anti-inflammatory, antimicrobial, anticancer, antidiarrheal, antihelmintic, CNS depressant, hepatoprotective, thrombolytic, antidiabetic, antioxidant, phagocytic and cytotoxic, and neuroprotective potential activities.

Discussion: Phytochemical analysis from different studies has reported Germacranolide, Sesquiterpene lactone, Flavonoid, Essential oil, Steroid, Diterpenoid, Melampolide, Sesquiterpene lactone, and Isoflavone glycoside as major compounds of Enhydra fluctuans Lour.

Conclusion: However, more research is needed to explore the mode of action of bioactive components of the plant and its therapeutic capabilities.

背景：Enhydra fluctuans Lour 是一种热带草本植物，俗称helencha 或harkuch，属于菊科。它是一种可食用的半水生草本植物，叶有锯齿，在世界各地普遍生长。Enhydrafluctuans 具有潜在的药理作用，可对抗炎症、癌症、腹泻、微生物感染、糖尿病等。

目的：本综述旨在提供有关 Enhydra fluctuans Lour 的植物学特征、分布、传统用途、化学成分以及药理活性的最新信息。

材料和方法：通过图书馆和电子搜索 PubMed、Elsevier、Google Scholar、Springer、Scopus、Web of Science、Wiley 在线图书馆，从科学期刊、书籍和全球公认的科学数据库中收集了有关 Enhydra 波动的最近更新的信息。所有与 Enhydra 相关的全文文章和摘要都经过筛选。本综述中精心挑选了最重要和最相关的文章进行研究。

结果：据报道，Enhydra fluctuans Lour 的粗提取物和分离的化合物对细胞保护、镇痛和抗炎、抗菌、抗癌、止泻、抗蠕虫、中枢神经系统抑制剂、保肝、溶栓、抗糖尿病、抗氧化剂、吞噬细胞和细胞毒性具有药理活性，和神经保护潜在活动。

讨论：来自不同研究的植物化学分析报告了 Germacranolide、倍半萜内酯、类黄酮、精油、类固醇、二萜、三聚氰胺、倍半萜内酯和异黄酮糖苷是 Enhydra fluctuans Lour 的主要化合物。

结论：然而，需要更多的研究来探索植物生物活性成分的作用方式及其治疗能力。