Purpose Dysphonia can be evaluated by both patient-reported quality of life instruments and objective acoustic and aerodynamic analyses. However, less is known about the association between the two metrics. The goal of this study was to perform a meta-analysis of the correlation of the Voice Handicap Index (VHI-30) with the following objective parameters: fundamental frequency, jitter, shimmer, harmonics to noise ratio, noise to harmonic ratio, maximum phonation time, and the Dysphonia Severity Index. Method A literature search was performed in the PubMed, Scopus, and Cumulative Index of Nursing and Allied Health Literature databases. Inclusion criteria were subjects age 18 years and older with voice complaints and assessed by both VHI-30 and objective voice analysis. Results A literature search resulted in 1,297 unique articles, of which 310 underwent full-text review and 17 studies were included in quantitative analysis. Significant pooled correlation was observed for VHI-30 total with jitter (.301 [.177; .416]), shimmer (.255 [.162; .344]), noise to harmonic ratio (.200 [.111; .285]), maximum phonation time (−.227 [−.352; −.094]), and Dysphonia Severity Index (−.254[−.455; −.0286]). Significant correlations were observed in 4/7 objective parameters with the Physical subscale, 3/7 with the Functional subscale, and 2/7 with the Emotional subscale. All significant correlations were negligible (0–.3) or low (.3–.5). Conclusions Results from meta-analysis showed that correlations between objective voice parameters and the VHI-30 were negligible or low. Further study is needed to determine if correlations vary by patient demographics or specific pathology.

中文翻译：

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语音障碍指数与客观语音分析之间关联的荟萃分析

目的发声困难可以通过患者报告的生活质量仪器和客观的声学和空气动力学分析来评估。然而，人们对这两个指标之间的关联知之甚少。本研究的目的是对语音障碍指数 (VHI-30) 与以下客观参数的相关性进行荟萃分析：基频、抖动、闪烁、谐波噪声比、噪声谐波比、最大发声时间和发音困难严重程度指数。 方法在 PubMed、Scopus 以及护理和联合健康文献累积索引数据库中进行了文献检索。纳入标准是年龄在 18 岁及以上、有声音抱怨的受试者，并通过 VHI-30 和客观声音分析进行评估。 结果文献检索共获得 1,297 篇独特文章，其中 310 篇进行了全文综述，17 项研究纳入了定量分析。观察到 VHI-30 总体与抖动 (.301 [.177; .416])、闪烁 (.255 [.162; .344])、噪声谐波比 (.200 [.111; .285) 的显着汇总相关性]）、最大发声时间（−.227 [−.352；−.094]）和发声困难严重程度指数（−.254[−.455；−.0286]）。观察到 4/7 的客观参数与身体分量表存在显着相关性，3/7 与功能分量表存在显着相关性，2/7 与情感分量表存在显着相关性。所有显着相关性均可忽略不计 (0–.3) 或较低 (0.3–.5)。 结论荟萃分析结果表明，客观语音参数与 VHI-30 之间的相关性可以忽略不计或很低。需要进一步研究以确定相关性是否因患者人口统计数据或特定病理学而变化。