This article aimed to demonstrate solution hospital wastewater due to more consumption of antibiotics, public concern has been significantly increased for usage, fates and occurrences of these emerging compounds in the environments and biota. Therefore, it does need more discoveries about occurrences and new treatment methods. Since the conventional treatment methods are low efficient on antibiotics, integration and combination of biological systems together or with an additional process has been shown that provided a better result. However, here, the potential of a full scale combined treating system with activated sludge-scoria biofilter (ASSB) was investigated for removal of ceftriaxone (CEF) and amoxicillin (AMX). To determine the potential biodegradability of proposed system, the solid-water distribution coefficient (Kd) was calculated. Overally, 118 samples were collected from three points; wastewater entering, exiting the activated sludge, and exiting the biofilter. To determine the amount of CEF and AMX antibiotics, the samples were analyzed using HPLC-UV. The results showed that the activated sludge system were able to eliminate the AMX and CEF antibiotics about 70.36 and 84.49%, respectively. In compare to activated sludge, the average mean of ASSB system for the removal efficiency were 87.53% (for AMX) and 93.17% (for CEF), respectively. As a result, it can be found that the efficiency of the combined activated sludge-biofilter system in removing of the low levels of antibiotics was more than individual activated system. The result of Kd revealed that AMX (with a Kd about 0.172) has lower tendency to biomass rather than CEF (with a Kd about 0.512). The ecological toxicity assessment guaranteed there is no risk for fish and daphnia when the activated sludge and also ASSB effluents to be discharged into the environment even without any diluting.

中文翻译：

---

混合系统成功地由医院污水中的活性污泥和生物滤池工艺组成：生态毒理学研究。

本文旨在展示由于消耗更多抗生素而导致的解决方案医院废水，公众对这些新兴化合物在环境和生物区系中的使用，命运和发生的关注大大增加。因此，它确实需要更多有关事件的发现和新的治疗方法。由于常规的治疗方法对抗生素的效率很低，因此显示出生物系统的整合和组合在一起或与其他方法结合后可提供更好的结果。然而，在这里，研究了带有活性污泥-污垢生物滤池（ASSB）的全尺寸联合处理系统去除头孢曲松（CEF）和阿莫西林（AMX）的潜力。为了确定所提出系统的潜在生物降解性，计算了固水分配系数（Kd）。总体而言，从三个方面收集了118个样本；废水进入，排出活性污泥和生物滤池。为了确定CEF和AMX抗生素的量，使用HPLC-UV对样品进行了分析。结果表明，活性污泥系统能够消除AMX和CEF抗生素，分别约为70.36％和84.49％。与活性污泥相比，ASSB系统去除效率的平均平均值分别为87.53％（对于AMX）和93.17％（对于CEF）。结果，发现结合的活性污泥-生物滤池系统去除低水平抗生素的效率比单独的激活系统高。Kd的结果表明，AMX（Kd约为0.172）比CEF（Kd约为0.512）具有更低的生物量趋势。