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Activated iridium oxide film (AIROF) electrodes for neural tissue stimulation.
Journal of Neural Engineering ( IF 3.7 ) Pub Date : 2020-10-12 , DOI: 10.1088/1741-2552/abb9bf
Rebecca A Frederick 1 , I Yasmine Meliane 2 , Alexandra Joshi-Imre 1 , Philip R Troyk 3 , Stuart F Cogan 1
Affiliation  

Objective . Iridium oxide films are commonly used as a high charge-injection electrode material in neural devices. Yet, few studies have performed in-depth assessments of material performance versus film thickness, especially for films grown on three-dimensional (instead of planar) metal surfaces in neutral pH electrolyte solutions. Further, few studies have investigated the driving voltage requirements for constant-current stimulation using activated iridium oxide (AIROF) electrodes, which will be a key constraint for future use in wirelessly powered neural devices. Approach . In this study, iridium microwire probes were activated by repeated potential pulsing in room temperature phosphate buffered saline (pH 7.1–7.3). Electrochemical measurements were recorded in three different electrolyte conditions for probes with different geometric surface areas (GSAs) as the AIROF thickness was increased. Main results . Maintaining an anodic potential bias during the i...

中文翻译:

用于神经组织刺激的活化氧化铱薄膜 (AIROF) 电极。

客观的 。氧化铱薄膜通常用作神经设备中的高电荷注入电极材料。然而,很少有研究对材料性能与薄膜厚度的关系进行深入评估,特别是对于在中性 pH 电解质溶液中在三维(而不是平面)金属表面上生长的薄膜。此外,很少有研究调查使用活性氧化铱(AIROF)电极进行恒流刺激的驱动电压要求,这将是无线供电神经设备未来使用的关键限制。方法 。在这项研究中,铱微丝探针通过在室温磷酸盐缓冲盐水(pH 7.1-7.3)中重复电势脉冲来激活。随着 AIROF 厚度的增加,在三种不同的电解质条件下记录具有不同几何表面积 (GSA) 的探针的电化学测量结果。主要成果。在i过程中保持阳极电位偏置...
更新日期:2020-10-13
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