Inflammation is commonly cited as a mechanism of delayed effects of acute radiation exposure (DEARE). Confirmation of its presence could provide significant insight to targeted use of treatments or mitigators of DEARE. We sought to quantify the presence of cellular inflammation in kidneys of non-human primates that developed acute and chronic kidney injury after a partial body irradiation exposure. We show herein that cellular inflammation is not found as a component of either acute or chronic kidney injury. Other mechanistic pathways of injury must be sought.

中文翻译：

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放射性肾病的非人类灵长类动物模型中缺乏细胞炎症。

炎症通常被认为是急性辐射暴露 (DEARE) 延迟效应的一种机制。确认其存在可以为有针对性地使用 DEARE 的治疗或缓解剂提供重要的见解。我们试图量化非人类灵长类动物肾脏中细胞炎症的存在，这些动物在部分身体照射暴露后发展为急性和慢性肾损伤。我们在此表明​​，细胞炎症不是急性或慢性肾损伤的组成部分。必须寻找其他机械损伤途径。