ABSTRACT

Objective: Research examining how different dimensions of acculturative beliefs and behaviors influence the risk of biological dysregulation among Latina/os is limited. This study examined associations between three types of acculturation and allostatic load (i.e. a multisystem index of biological dysregulation) across gender and Latina/o ethnic groups. Multiplicative models were also included in order to determine whether immigrant generation moderates acculturation-allostatic load relationships.

Design: Data were drawn from the Hispanic Community Health Study/ Study of Latina/os. The sample consisted of 11,841 Latina/os from five ethnic groups: Cuban, Puerto Rican, Dominican, Mexican, and South/Central American. The measure for allostatic load was derived from 15 biomarker and anthropometric measures that were designed to capture cardiometabolic risk, glucose metabolism, cardiopulmonary function, inflammation, and organ function. Acculturation measures, immigrant generation, gender, ethnic background, and other covariates were derived from self-reports. Survey corrected ordinary least squares regressions were used to assess relationships between different dimensions of acculturation and allostatic load.

Results: Results demonstrate dimensions of acculturation play a significant role in the risk of biological dysregulation for Latina/os with divergent results across gender and ethnic background. Estimates from the multiplicative models show immigrant generation moderates acculturation-allostatic load relationships, and relationships are dependent on gender and ethnic background.

Conclusion: The study contributes to the understanding of how different dimensions of acculturation, as well as other important structural determinants of health, influence the risk of biological dysregulation among Latina/os. Finding from this study can inform targeted strategies designed to reduce the physiological consequences of chronic stress among Latina/os.

摘要

目的：关于文化适应信念和行为的不同维度如何影响拉丁裔 / os 生物失调风险的研究是有限的。这项研究检查了跨性别和拉丁裔/o 族群的三种文化适应和异能负荷（即生物失调的多系统指数）之间的关联。乘法模型也包括在内，以确定移民一代是否会缓和文化适应-平衡负荷关系。

设计：数据来自西班牙裔社区健康研究/拉丁裔/os 研究。样本包括来自五个种族的 11,841 名拉丁裔/os：古巴人、波多黎各人、多米尼加人、墨西哥人和南/中美洲人。静态负荷的测量来自 15 种生物标志物和人体测量测量，这些测量旨在捕捉心脏代谢风险、葡萄糖代谢、心肺功能、炎症和器官功能。文化适应措施、移民一代、性别、种族背景和其他协变量来自自我报告。调查校正的普通最小二乘回归用于评估不同维度的文化适应和异位负荷之间的关系。

结果：结果表明，文化适应的维度在拉丁裔 / os 生物失调的风险中发挥着重要作用，不同性别和种族背景的结果不同。乘法模型的估计表明，移民一代缓和了文化适应-平衡负荷关系，并且关系取决于性别和种族背景。

结论：该研究有助于了解文化适应的不同维度以及其他重要的健康结构决定因素如何影响拉丁裔 / os 生物失调的风险。这项研究的发现可以为旨在减少拉丁裔/os中慢性压力的生理后果的有针对性的策略提供信息。