AIM To compare the effect of two calcium silicate-based (Endoseal MTA and EndoSequence BC Sealer) and an epoxy resin-based (AH Plus) root canal sealer on postoperative pain following root canal treatment. METHODOLOGY Patients (n=90) having one first or second molar tooth diagnosed with asymptomatic irreversible pulpitis were randomly divided into three groups according to the sealer used (n=30) and were treated by two endodontists having at least ten years of experience. All patients received a single-visit root canal treatment. After the treatments, postoperative pain scores and analgesic intake were recorded at 6, 12, 24 and 48 hours, and 3, 4, 5, 6, and 7 days. The data were statistically analyzed with nonparametric Kruskal-Wallis tests (for the comparisons of the age and VAS scores), Friedman tests (for the assessments of the changes in pain scores over time), chi-squared tests (for the comparisons of categorical variables), and Spearman's correlation test (for the correlation assessments of the age and gender factors with postoperative pain) (α=0.05). RESULTS There were no significant differences among the groups in terms of postoperative pain at any time points assessed (P>0.05) nor for analgesic intake of patients among the groups (P>0.05). Analgesic intake decreased significantly after 12 hours in all groups (P<0.05). CONCLUSIONS The sealers tested in this study had similar levels of postoperative pain and were associated with similar intake of analgesics.

中文翻译：

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两种钙基和一种基于环氧树脂的根管封闭剂对术后骨痛的影响：随机对照管。

目的比较两种硅酸钙基（Endoseal MTA和EndoSequence BC Sealer）和环氧树脂基（AH Plus）根管封闭剂对根管治疗术后疼痛的影响。方法论根据诊断所使用的封闭剂（n = 30）将被诊断为无症状不可逆性牙髓炎的第一颗或第二颗磨牙的患者（n = 90）随机分为三组，并由两名具有至少十年经验的牙髓治疗。所有患者均接受单次根管治疗。治疗后，分别在第6、12、24和48小时以及第3、4、5、6和7天记录术后疼痛评分和止痛药的摄入量。使用非参数Kruskal-Wallis检验对数据进行统计分析（以比较年龄和VAS得分），Friedman检验（用于评估随时间变化的疼痛评分），卡方检验（用于比较类别变量）和Spearman关联检验（用于评估年龄和性别因素与术后疼痛的关联性）（α = 0.05）。结果各组之间在评估的任何时间点的术后疼痛方面均无显着差异（P> 0.05），各组患者的镇痛摄入量也无显着差异（P> 0.05）。所有组在12小时后镇痛剂摄入量均显着下降（P <0.05）。结论本研究中测试的封闭剂具有相似的术后疼痛水平，并且与止痛药的摄入量相似。相关测试（用于评估年龄和性别因素与术后疼痛的相关评估）（α= 0.05）。结果各组之间在评估的任何时间点的术后疼痛方面均无显着差异（P> 0.05），各组患者的镇痛摄入量也无显着差异（P> 0.05）。所有组在12小时后镇痛剂摄入量均显着下降（P <0.05）。结论本研究中测试的封闭剂具有相似的术后疼痛水平，并且与止痛药的摄入量相似。相关测试（用于评估年龄和性别因素与术后疼痛的相关评估）（α= 0.05）。结果各组之间在评估的任何时间点的术后疼痛方面均无显着差异（P> 0.05），各组患者的镇痛摄入量也无显着差异（P> 0.05）。所有组在12小时后镇痛剂摄入量均显着下降（P <0.05）。结论本研究中测试的封闭剂具有相似的术后疼痛水平，并且与止痛药的摄入量相似。所有组在12小时后镇痛剂摄入量均显着下降（P <0.05）。结论本研究中测试的封闭剂具有相似的术后疼痛水平，并且与止痛药的摄入量相似。所有组在12小时后镇痛剂摄入量均显着下降（P <0.05）。结论本研究中测试的封闭剂具有相似的术后疼痛水平，并且与止痛药的摄入量相似。