Objective: The present study aimed to characterize the association of perceived gender discrimination and illicit drug use among a sample of African American (AA) and European American (EA) adolescent girls and young women. Method: Data were drawn from a high-risk family study of alcohol use disorder of mothers and their offspring (N = 735). Multinomial regressions were used to examine whether experience of offspring and maternal gender discrimination were associated with offspring illicit drug use (cannabis, cocaine, ecstasy, PCP, opiates, hallucinogens, solvents, sedatives, or inhalants). Outcomes included offspring age of drug use initiation (age ≤ 14) and lifetime heavy drug use (≥ 50 times) of 1 or more illicit substances. Interactions between race and offspring gender discrimination were modeled to assess for race differences. Results: Results revealed that gender discrimination was associated with a greater likelihood of offspring early initiation (relative risk ratio [RRR] = 2.57, 95% CI [1.31, 5.03]) versus later initiation (RRR = 1.33, 95% CI [0.80, 2.24]). Offspring gender discrimination was associated with offspring heavy drug use (RRR = 2.09, 95% CI [1.07, 4.06]) and not associated with moderate/light use (RRR = 1.44, 95% CI [0.86, 2.42]), but post hoc tests revealed no significant group differences. Conclusions: Findings suggest that perceived offspring gender discrimination is associated with early drug use initiation. Gender discrimination, particularly at an early age, has a potential to cause harm, including drug use. Implementation of policies that foster environments that eliminate gender bias and discrimination at an early age should be prioritized. Gender-responsive treatment merits consideration by substance use treatment providers. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

中文翻译：

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非洲裔美国人和欧洲裔美国青少年和新兴成年人的性别歧视和非法药物使用。

目的：本研究旨在描述非洲裔美国人 (AA) 和欧洲裔美国人 (EA) 青春期女孩和年轻女性样本中感知到的性别歧视与非法药物使用之间的关联。方法：数据来自一项关于母亲及其后代酒精使用障碍的高风险家庭研究（N = 735）。多项回归用于检查后代和母亲性别歧视的经历是否与后代非法药物使用（大麻、可卡因、摇头丸、PCP、鸦片制剂、致幻剂、溶剂、镇静剂或吸入剂）相关。结果包括子女开始吸毒的年龄（年龄≤14岁）和终生重度吸毒（≥50次）一种或多种非法物质。种族和后代性别歧视之间的相互作用被建模以评估种族差异。结果：结果显示，与较晚开始（RRR = 1.33, 95% CI [0.80, 2.24]）相比，性别歧视与后代早期开始的可能性更大（相对风险比 [RRR] = 2.57, 95% CI [1.31, 5.03]）相关）。后代性别歧视与后代重度吸毒有关（RRR = 2.09, 95% CI [1.07, 4.06]），与中度/轻度吸毒无关（RRR = 1.44, 95% CI [0.86, 2.42]），但事后测试显示没有显着的组间差异。结论：研究结果表明，感知到的后代性别歧视与早期吸毒开始有关。性别歧视，特别是在幼年时期，有可能造成伤害，包括吸毒。应优先实施促进消除早期性别偏见和歧视的环境的政策。对性别敏感的治疗值得物质使用治疗提供者考虑。（PsycInfo 数据库记录 (c) 2020 APA，保留所有权利）。