New HIV infections associated with injection drug use are of major concern in rural US communities. This study explores acceptability of, consent for, and uptake of free at-home HIV testing among people who use drugs (PWUD) in one of the nation’s epicenters for drug-related harms and HIV vulnerability: Rural Central Appalachia. Eligible participants were 18–35 years old, lived in Appalachian Kentucky, and reported using opioids to get high in the previous 30 days. A majority reported being likely (63.6%, 96/151) to take a free at-home HIV tests and 66.9% (101/151) consented to receive one. Among those who were randomly selected to receive a Home Access HIV-1 test kit (n = 37), 37.8% mailed in blood spots and 21.6% called to receive results. This study provides evidence that PWUD may be willing to take an at-home test, but other barriers may inhibit actual completion.

与注射吸毒有关的新 HIV 感染是美国农村社区的主要关注点。本研究探讨了在全国药物相关危害和 HIV 易感性的中心之一：阿巴拉契亚中部农村地区，吸毒者 (PWUD) 的可接受性、同意和接受免费家庭 HIV 检测。符合条件的参与者年龄在 18-35 岁之间，居住在阿巴拉契亚肯塔基州，并报告在过去 30 天内使用阿片类药物达到高潮。大多数人报告可能（63.6%，96/151）接受免费的家庭艾滋病毒检测，66.9%（101/151）同意接受一次。在被随机选择接受 Home Access HIV-1 检测试剂盒（n = 37）的人中，37.8% 的人邮寄血斑，21.6% 的人打电话要求接收结果。这项研究提供了证据表明 PWUD 可能愿意在家进行​​测试，