The Nord-Trøndelag Health Study (The HUNT Study) is a large health survey population study in the county of Trøndelag, Norway. The survey has been repeated four times in about 10-year intervals. In the HUNT3 survey (2006–2008), we collected 28,000 samples for trace element analysis. Blood samples from 758 healthy persons without known occupational exposure were selected for multielement analysis of a small sample of blood (0.25 mL). The aim of the study was to determine the minimum blood volume that can be used for the analytical procedure and to compare our results with previously published results of similar surveys in healthy populations. Samples were digested and the concentration of selected trace elements was determined by ICP-MS. We report results on essential elements (B, Co, Cu, Mn, Se and Zn) as well as non-essential elements (As, Be, Br, Cd, Cs, In, La, Pb, Hg, Nd, Ni, Nb, Pd, Pt, Sm, Ta and Sn). Results are similar to previous studies on the HUNT3 population, and with a few exceptions, our data compares very well with results obtained in recent studies from other countries. We wanted to test a minimum volume of blood in a large-scale analytical program. For a number of nonessential elements, our results were below the limit of detection. We suggest that future studies using similar ICP-MS equipment as analytical tool should use at least 0.5 mL of blood.

Nord-Trøndelag 健康研究（HUNT 研究）是挪威 Trøndelag 县的一项大型健康调查人口研究。该调查在大约 10 年的时间间隔内重复了四次。在 HUNT3 调查（2006-2008 年）中，我们收集了 28,000 个样品进行微量元素分析。选择了 758 名没有已知职业暴露的健康人的血样，对少量血样 (0.25 mL) 进行多元素分析。该研究的目的是确定可用于分析程序的最小血量，并将我们的结果与之前发表的健康人群类似调查结果进行比较。对样品进行消解，并通过 ICP-MS 确定所选痕量元素的浓度。我们报告了必需元素（B、Co、Cu、Mn、Se 和 Zn）以及非必需元素（As、Be、Br、Cd、Cs、In、La、Pb、Hg、Nd、Ni、Nb、Pd、Pt、Sm、Ta 和 Sn）。结果与之前对 HUNT3 人群的研究相似，除了少数例外，我们的数据与其他国家最近研究中获得的结果相比非常好。我们想在大规模分析程序中测试最小量的血液。对于许多非必需元素，我们的结果低于检测限。我们建议使用类似 ICP-MS 设备作为分析工具的未来研究应使用至少 0.5 mL 的血液。对于许多非必需元素，我们的结果低于检测限。我们建议使用类似 ICP-MS 设备作为分析工具的未来研究应使用至少 0.5 mL 的血液。对于许多非必需元素，我们的结果低于检测限。我们建议使用类似 ICP-MS 设备作为分析工具的未来研究应使用至少 0.5 mL 的血液。