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Music as a Sleep Aid in Fibromyalgia
Pain Research and Management ( IF 2.5 ) Pub Date : 2014 , DOI: 10.1155/2014/272108
Larry M Picard 1, 2 , Lee R Bartel 1 , Allan S Gordon 1, 2 , Davor Cepo 1 , Qi Wu 2 , Leah R Pink 2
Affiliation  

BACKGROUND: Interventions to improve sleep in fibromyalgia may generalize to improvements in multiple symptom domains. Delta-embedded music, pulsating regularly within the 0.25 Hz to 4 Hz frequency band of brain wave activity, has the potential to induce sleep.OBJECTIVES: To assess the effects of a delta-embedded music program over four weeks for sleep induction in patients with fibromyalgia.METHODS: The present unblinded, investigator-led pilot study used a within-subject design. Analysis was based on 20 individuals with fibromyalgia who completed the study, of the 24 recruited into the study. The primary outcome variables were the change from baseline in Fibromyalgia Impact Questionnaire (FIQ) and Jenkins Sleep Scale scores. A patient global impression of change was measured on a seven-point Likert scale. Secondary outcome measures, comprised of items 5, 6 and 7 of the FIQ, were used as indicators of pain, tiredness and being tired on awakening.RESULTS: The FIQ median score of 76.4 (95% CI 61.3 to 82.1) at baseline improved to 60.3 (95% CI 53.1 to 72.0; P=0.004). The Jenkins Sleep Scale median value of 17.5 (95% CI 15.5 to 18.5) at baseline fell to 12.5 (95% CI 8.5 to 14.5; P=0.001) at study completion. The outcomes of the patient global impression of change ratings were mostly positive (P=0.001). Being tired on awakening declined significantly from a median of 9.0 (95% CI 8.0 to 10.0) to 8.0 (95% CI 5.5 to 9.0; P=0.021). However, there was no significant improvement in pain level (baseline median 7.5 [95% CI 7.0 to 8.5] versus study completion median 7.0 [95% CI 6.5 to 8.0]; P=0.335) or tiredness (baseline median 9.0 [95% CI 8.0 to 9.5] versus study completion median 8.0 [95% CI 6.0 to 8.5]; P=0.061). There were no serious adverse events.CONCLUSIONS: Delta-embedded music is a potential alternative therapy for fibromyalgia.

中文翻译:

音乐作为纤维肌痛的睡眠帮助

背景:改善纤维肌痛睡眠的干预措施可能会普遍改善多种症状。Delta嵌入音乐在脑电波活动的0.25 Hz至4 Hz频带内有规律地脉动,具有诱发睡眠的潜力。目标:评估为期4周的Delta嵌入式音乐程序对睡眠诱发的患者的影响纤维肌痛方法:目前,由研究者主导的一项无盲实验研究使用的是受试者内部设计。分析基于完成研究的20名患有纤维肌痛的个体中的24名个体进行。主要结局变量是纤维肌痛影响问卷(FIQ)和詹金斯睡眠量表评分与基线相比的变化。对患者的整体变化印象以利克特(Likert)七分制进行了测量。次要结果指标 结果由FIQ的第5、6和7项组成,用于指示疼痛,疲倦和觉醒时的疲倦。结果:基线时FIQ的中位数评分为76.4(95%CI从61.3到82.1)提高到60.3(95%) CI 53.1至72.0; P = 0.004)。在研究完成时,Jenkins睡眠量表中位值为17.5(95%CI为15.5至18.5)降至12.5(95%CI为8.5至14.5; P = 0.001)。患者对变化定级的整体印象大多为阳性(P = 0.001)。觉醒时疲倦从中位数9.0(95%CI 5.5至9.0; 95%CI 5.5至9.0; P = 0.021)显着下降。但是,疼痛水平(基线中位数7.5 [95%CI 7.0至8.5]相对于研究完成中位数7.0 [95%CI 6.5至8.0]; P = 0.335)或疲劳(基线中位数9.0 [95%CI])无明显改善。 8.0至9.5],而研究完成中位数为8。0 [95%CI 6.0至8.5];P = 0.061)。没有严重的不良事件。结论:Delta嵌入音乐是一种可能的纤维肌痛替代疗法。
更新日期:2020-09-25
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