Background: Herbicides are very beneficial in the crop yield with the aid of controlling weeds within the agriculture, but several herbicides are chronic in soil.

Objective: In this study, nanoparticles and the packages of synthesized novel silica nanoparticles were studied for the preconcentration of herbicides.

Methods: These nanoparticles prepared by the Stöber mechanism were purified and functionalized. Nanoparticles thus prepared successfully were used as supporting material for the preconcentration of residues of herbicides in the water.

Results: Preconcentration was achieved by preparing the silica-based solid-phase-extraction cartridges. Nanoparticles used for this purpose were within the range of 50-250 nm. An SPE cartridge was prepared by packing 200 mg of silica nanoparticle in the empty cartridge of diameter 5.5 cm and length 0.6 cm in between PTFE frits. Aqueous solutions of 0.1 μg/ml of herbicides were prepared separately, and 10 ml of the solution was passed through the cartridge at the rate of 0.2 ml/min. After passing 10 ml volume of the aqueous solution, residues adsorbed on the cartridge were eluted using 2 ml of acetonitrile. The eluate was injected to determine the herbicide residue adsorbed on the SPE cartridge.

Conclusion: In the study, it was found that greater than 90% of the herbicide residues were trapped on silica nanoparticle-based SPE cartridge. An analytical method was developed for the simultaneous determination of these herbicides. The residues were quantified by LC-MS/MS with ESI mode.

背景：除草剂通过控制农业中的杂草对作物产量非常有益，但是几种除草剂在土壤中是慢性的。

目的：在这项研究中，研究了纳米颗粒和合成的新型二氧化硅纳米颗粒的包装，以进行除草剂的预浓缩。

方法：将这些通过Stöber机理制备的纳米颗粒进行纯化和功能化。如此成功制备的纳米颗粒被用作支持剂，用于对水中除草剂的残留物进行预浓缩。

结果：通过制备二氧化硅基固相萃取柱实现了预浓缩。用于该目的的纳米颗粒在50-250nm的范围内。通过将200 mg二氧化硅纳米颗粒填充在PTFE熔块之间直径为5.5 cm，长度为0.6 cm的空盒中来制备SPE盒。分别制备0.1μg/ ml除草剂的水溶液，使10 ml溶液以0.2 ml / min的速度通过药筒。通过10 ml体积的水溶液后，使用2 ml乙腈洗脱吸附在小柱上的残留物。注入洗脱液以确定吸附在SPE柱上的除草剂残留物。

结论：在研究中，发现超过90％的除草剂残留物被捕获在基于二氧化硅纳米粒子的SPE柱上。开发了一种同时测定这些除草剂的分析方法。残留物通过ESI模式的LC-MS / MS进行定量。