Parthenium hysterophorus (Compositae), an obnoxious weed, was investigated thoroughly for its chemical constituents. We isolated a large number of pseudoguaianolides and other compounds. Many of the isolates are new natural products. Parthenin, the major pseudoguaianolide, was synthetically converted to its various analogues. Some of the constituents of the plant and of the prepared analogues were found to possess significant antibacterial and anticancer properties. Here, we review our phytochemical research on Parthenium hysterophorus informing of our work on the isolation, structure elucidation, synthetic modifications, and bioevaluation of its chemical constituents.

对一种讨厌的杂草Parthenium hysterophorus（Compositae）进行了彻底的化学成分研究。我们分离了许多假愈创木酚内酯和其他化合物。许多分离株是新的天然产物。主要的伪愈创木酚内酯Parthenin被合成为各种类似物。发现植物的某些成分和制备的类似物具有显着的抗菌和抗癌特性。在这里，我们回顾了我们对Parthenium hysterophorus的植物化学研究，为我们在分离，结构阐明，合成修饰以及对其化学成分进行生物评价方面的工作提供了信息。