While hospital admissions for myocardial infarction (MI) and pulmonary embolism (PE) are decreased during the COVID-19 pandemic, controversy remains about respective complication and mortality rates. This study evaluated admission rates, complications, and intrahospital mortality for selected life-threatening cardiovascular emergencies (MI, PE, and acute aortic dissection (AAD)) during COVID-19-associated restrictive social measures (RM) in Styria, Austria. By screening a patient information system for International Statistical Classification of Diseases and Related Health Problems (ICD) diagnosis codes covering more than 85% of acute hospital admissions in the state of Styria (~1.24 million inhabitants), we retrospectively identified patients with admission diagnoses for MI (I21, I22), PE (I26), and AAD (I71). Rates of complications such as cardiogenic shock and cardiopulmonary resuscitation, treatment escalations (thrombolysis for PE), and mortality were analyzed by patient chart review during 6 weeks following onset of COVID-19 associated RM, and during respective time frames in the years 2016 to 2019. 1,668 patients were included. Cumulative admissions for MI, PE and AAD decreased (RR 0.77; p<0.001) during RM compared to previous years. In contrast, intrahospital mortality increased by 65% (RR 1.65; p = 0.041), mainly driven by mortality following MI (RR 1.80; p = 0.042). PE patients received more frequently thrombolysis treatment (RR 3.63; p = 0.006), while rates of cardiogenic shock and cardiopulmonary resuscitation remained unchanged. Of 226 patients hospitalized during RM, 81 patients with suspected COVID-19 disease were screened for SARS-CoV-2 infection with only 5 testing positive. Thus, cumulative hospital admissions for cardiovascular emergencies decreased during COVID-19 associated RM while intrahospital mortality increased.

尽管在COVID-19大流行期间因心肌梗塞（MI）和肺栓塞（PE）入院的人数有所减少，但有关并发症和死亡率的争议仍然存在。这项研究评估了奥地利施蒂利亚州与COVID-19相关的限制性社会措施（RM）期间某些危及生命的心血管紧急情况（MI，PE和急性主动脉夹层（AAD））的入院率，并发症和院内死亡率。通过针对国际疾病和相关健康问题统计分类（ICD）诊断代码的患者信息系统进行筛查，该代码覆盖了施蒂里亚州（〜124万居民）超过85％的急性住院患者，我们回顾性地确定了接受以下诊断的患者： MI（I21，I22），PE（I26）和AAD（I71）。在COVID-19相关性RM发作后的6周内以及在2016年至2019年的各个时间范围内，通过患者图表审查分析了诸如心源性休克和心肺复苏，治疗升级（PE血栓溶解）等并发症的发生率包括1,668例患者。与前几年相比，RM期间MI，PE和AAD的累计入院率下降（RR 0.77; p <0.001）。相比之下，医院内死亡率增加了65％（RR 1.65； p = 0.041），这主要是由MI后的死亡率（RR 1.80; p = 0.042）驱动。PE患者接受溶栓治疗的频率更高（RR 3.63； p = 0.006），而心源性休克和心肺复苏的发生率保持不变。在RM期间住院的226名患者中，对81名疑似COVID-19疾病的患者进行了SARS-CoV-2感染筛查，仅有5项检测呈阳性。因此，在COVID-19相关性RM期间，因心血管急诊而累积的住院人数减少，而院内死亡率增加。