Abstract

Human visual cortex contains many retinotopic and category-specific regions. These brain regions have been the focus of a large body of functional magnetic resonance imaging research, significantly expanding our understanding of visual processing. As studying these regions requires accurate localization of their cortical location, researchers perform functional localizer scans to identify these regions in each individual. However, it is not always possible to conduct these localizer scans. Here, we developed and validated a functional region of interest (ROI) atlas of early visual and category-selective regions in human ventral and lateral occipito-temporal cortex. Results show that for the majority of functionally defined ROIs, cortex-based alignment results in lower between-subject variability compared to nonlinear volumetric alignment. Furthermore, we demonstrate that 1) the atlas accurately predicts the location of an independent dataset of ventral temporal cortex ROIs and other atlases of place selectivity, motion selectivity, and retinotopy. Next, 2) we show that the majority of voxel within our atlas is responding mostly to the labeled category in a left-out subject cross-validation, demonstrating the utility of this atlas. The functional atlas is publicly available (download.brainvoyager.com/data/visfAtlas.zip) and can help identify the location of these regions in healthy subjects as well as populations (e.g., blind people, infants) in which functional localizers cannot be run.

中文翻译：

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人类枕颞视觉皮层的概率功能图谱。

 抽象的

人类视觉皮层包含许多视网膜专题和类别特异性区域。这些大脑区域一直是大量功能磁共振成像研究的焦点，显着扩展了我们对视觉处理的理解。由于研究这些区域需要准确定位其皮质位置，因此研究人员进行功能定位器扫描来识别每个人的这些区域。然而，并不总是可以进行这些定位器扫描。在这里，我们开发并验证了人类腹侧和外侧枕颞叶皮层早期视觉和类别选择区域的功能感兴趣区域（ROI）图谱。结果表明，对于大多数功能定义的 ROI，与非线性体积对齐相比，基于皮层的对齐导致受试者之间的变异性较低。此外，我们证明：1）该图集准确地预测了腹侧颞叶皮层 ROI 的独立数据集和其他位置选择性、运动选择性和视网膜局部图集的位置。接下来，2）我们表明，我们的图谱中的大多数体素主要对遗漏的主题交叉验证中的标记类别做出响应，证明了该图谱的实用性。功能图谱是公开可用的 (download.brainvoyager.com/data/visfAtlas.zip)，可以帮助识别健康受试者以及无法运行功能定位器的人群（例如盲人、婴儿）中这些区域的位置。