Our laboratory has reported with near-infrared spectroscopy (NIRS) that prefrontal oxygenated-hemoglobin concentration (Oxy-Hb), measured as index of regional cerebral blood flow, increased prior to and at the onset of arbitrary (i.e. non-cued) ergometer exercise in laboratory environment. In the current study, we hypothesized that naturally-occurring overground locomotion, despite "very light" motor effort as indicated by Borg scale of 8.0 ± 0.3, likewise causes such pre-exercise activation of the prefrontal cortex. Using wireless NIRS, this study examined how early and to what extent prefrontal activity changed prior to the onset of arbitrary walking in 13 subjects. Prefrontal Oxy-Hb increased 2 s prior to the onset of arbitrary walking and the increased Oxy-Hb reached a peak at 5 s from walking onset. The pre-exercise and initial increase in prefrontal Oxy-Hb was absent when overground walking was forced to start by cue. The difference in the Oxy-Hb response between arbitrary and cued start, which was considered to be related to central command, became significant 2 s before walking onset, preceding the difference in the heart rate (HR) response by 8 s and demonstrating a positive relationship with the HR difference in 69% of subjects. Imagery of arbitrary walking was likewise able to increase prefrontal oxygenation to the same extent as actual walking. Thus it is likely that prefrontal oxygenation increases prior to the onset of naturally-occurring walking in daily life, despite "very light" effort. The increased prefrontal oxygenation may contribute at least partly to cardiac adjustment, synchronized with the beginning of motor performance.

中文翻译：

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在人类进行地面运动之前和开始时，额前氧合增加。

我们的实验室用近红外光谱仪（NIRS）报告说，在进行任意（即无提示的）测力计运动之前和发作之前，前额氧合血红蛋白浓度（Oxy-Hb）以区域脑血流量指数衡量在实验室环境中。在当前的研究中，我们假设自然发生的地面运动，尽管Borg评分为8.0±0.3表示“非常轻”的运动，同样会引起前额叶皮层的这种运动前激活。这项研究使用无线NIRS检查了13名受试者在任意行走开始之前额叶活动的早期程度和程度。在任意行走开始前2 s，前额叶Oxy-Hb升高，而在行走开始5 s时，升高的Oxy-Hb达到峰值。当由于提示被迫开始地面行走时，前额额Oxy-Hb的运动前和初始增加不存在。被认为与中央命令有关的任意和提示启动之间的Oxy-Hb反应差异在行走前2 s变得显着，先于心率（HR）响应差异8 s并显示出阳性与69％的受试者的HR差异之间的关系。任意行走的图像同样能够使前额氧合增加到与实际行走相同的程度。因此，尽管付出了“非常轻”的努力，但在日常生活中自然行走之前，额叶前氧合可能增加。额叶前氧合增加可能至少部分有助于心脏调节，