Three-dimensional (3D) porous laser-guided graphene (LGG) electrodes on elastomeric substrates are of great significance for developing flexible functional electronics. However, the high sheet resistance and poor mechanical properties of LGG sheets obstruct their full exploitation as electrode materials. Herein, we applied 2D MXene nanosheets to functionalize 3D LGG sheets via a C–O–Ti covalent crosslink to obtain an LGG-MXene hybrid scaffold exhibited high conductivity and improved electrochemistry with fast heterogeneous electron transfer (HET) rate due to the synergistic effect between LGG and MXene. Then we transferred the obtained hybrid scaffold onto PDMS to engineer a smart, flexible, and stretchable multifunctional sensors-integrated wound bandage capable of assessing uric acid (UA), pH, and temperature at the wound site. The integrated UA sensor exhibited a rapid response toward UA in an extended wide range of 50–1200 μM with a high sensitivity of 422.5 μA mM⁻¹ cm⁻² and an ultralow detection limit of 50 μM. Additionally, the pH sensor demonstrated a linear Nernstian response (R² = 0.998) with a high sensitivity of −57.03 mV pH⁻¹ in the wound relevant pH range of 4–9. The temperature sensor exhibited a fast and stable linear resistive response to the temperature variations in the physiological range of 25–50 °C with an excellent sensitivity and correlation coefficient of 0.09% ⁰C⁻¹ and 0.999, respectively. We anticipate that this stretchable and flexible smart bandage could revolutionize wound care management and have profound impacts on the therapeutic outcomes.

弹性体基板上的三维（3D）多孔激光导引石墨烯（LGG）电极对于开发柔性功能电子器件具有重要意义。但是，LGG薄板的高薄层电阻和较差的机械性能阻碍了它们充分用作电极材料。在本文中，我们应用2D MXene纳米片材通过C–O–Ti共价交联功能将3D LGG片材功能化，从而获得LGG-MXene杂种支架，该支架具有高电导率并由于电化学反应之间的协同效应而具有快速异质电子转移（HET）速率的改进的电化学性能LGG和MXene。然后，我们将获得的杂种支架转移到PDMS上，以设计出一种智能，灵活且可拉伸的多功能传感器-集成了伤口绷带​​的伤口绷带，该绷带能够评估伤口部位的尿酸（UA），pH和温度。^-1 cm ^-2和50μM的超低检测限。此外，pH传感器在4-9的伤口相关pH范围内显示出线性的Nernstian响应（R ²  = 0.998），灵敏度为-57.03 mV pH ^-1。温度传感器对25–50°C的生理范围内的温度变化表现出快速稳定的线性电阻响应，灵敏度和相关系数分别为0.09％⁰C ^-1和0.999，具有出色的灵敏度。我们预计，这种可伸展且灵活的智能绷带将彻底改变伤口护理管理，并对治疗效果产生深远影响。