In the framework of sustainable development, there is an increasing need to assess, model, and optimize the implementation of renewable energy technologies such as the anaerobic co-digestion of different organic residues. This work studied the influence of some independent parameters on the production of biogas through anaerobic co-digestion of specific organic residues widely available in Colombia (pig manure -PM-, sewage sludge –SS–, organic fraction of municipal solid waste -OFMSW-, residues from the bottled fruit drinks industry -RBFDI-, and cocoa industry residue -CIR-). The Biochemical Methane Potential (BMP) of different mixtures was assessed through a Box-Behnken experimental design, where the parameters were: volatile solids content (0.5, 1.25 and 2 g VS), C/N ratio (25, 35 and 45), and nitrogen source (0% for only SS, 50% both residues PM and SS, and 100% if only PM). The results allowed empirical model building by using second-order polynomial and MARSplines. According to the maximization, the best mixture for biogas production is the one containing RBFDI, OFMSW, and SS, a C/N ratio of 40 and 0.5 g VS; the estimated production was around 382.17 ml CH₄ g⁻¹ VS, MARSplines demonstrated to have the best predictions values and the highest determination coefficient (94–97%). Moreover, it was evidenced that the content of g VS is a critical variable on the methane production, C/N ratio must be in average values, and both nitrogen sources are suitable to be used in the co-digestion process depending on the availability of the area of interest.

在可持续发展的框架内，越来越需要评估，建模和优化可再生能源技术的实施，例如不同有机残留物的厌氧共消化。这项工作通过厌氧共消化哥伦比亚广泛使用的特定有机残留物（猪粪-PM-，污泥-SS-，城市固体废物的有机物-OFMSW-，瓶装水果饮料行业的残留物-RBFDI-和可可行业的残留物-CIR-）。通过Box-Behnken实验设计评估了不同混合物的生化甲烷潜力（BMP），参数为：挥发性固体含量（0.5、1.25和2 g VS），C / N比（25、35和45），和氮源（仅SS为0％，PM和SS均为50％，如果只有PM，则为100％）。结果允许通过使用二阶多项式和MARSplines建立经验模型。根据最大化，用于沼气生产的最佳混合物是包含RBFDI，OFMSW和SS，C / N比为40和0.5 g VS的混合物。估计产量约为382.17毫升CH₄ g ^-1 VS，MARSplines被证明具有最佳的预测值和最高的确定系数（94–97％）。此外，有证据表明，g VS的含量是甲烷产量的关键变量，C / N比必须取平均值，并且两种氮源都适合用于共消化过程，具体取决于甲烷的可用性。感兴趣的区域。