Radiation monitoring is an important radiation safety measure implemented at the hydrometallurgical plant of the Stepnogorsk mining and chemical combine (HMP SMCC, Republic of Kazakhstan). Follow-up of the workers and their regular medical examinations has laid the basis to create a cohort with the potential to be used in radiation epidemiology. The aim of current pilot study was to analyze the dose forming factors for workers of HMP SMCC. For this, bioassays samples collected from 54 workers employed at eight HMP workshops were measured using the "Agilent 7800 ICP-MS" mass spectrometer. Three years later, measurements were repeated for four workers with the highest concentrations of uranium in urine. The results of site-specific measurements of dose rates, long-lived alpha-particle activity concentrations and equivalent equilibrium volume activity of radon were derived from the archive of the HMP SMCC Service of Radiation and Toxic Safety and analyzed to fully evaluate the radiation situation at those workplaces. Maximum urine uranium concentrations were measured for workers at the extraction workshop and mechanical repair shop (up to 26.7 µg/L and 14.6 µg/L, respectively). Urinary uranium from workers employed at other sites was mainly (for about 72% of the samples) in the range of values that may occur in natural conditions (< 0.4 µg/L). A wide individual variability in uranium concentration in urine samples (from 60% to 200% of CV) was found. A linear dependence of cumulative effective dose on work experience was found with a slope of 7.5 mSv per year. This slope did not depend on working place. For the investigated workers, cumulative effective doses of workers were found in the range of low (< 100 mSv) and medium doses (100–500 mSv). It is concluded that the newly created cohort of HMP SMCC workers has the potential to improve the knowledge on health effects from low- and medium doses of ionizing radiation.

辐射监测是Stepnogorsk采矿和化学联合工厂（HMP SMCC，哈萨克斯坦共和国）的湿法冶金工厂实施的一项重要的辐射安全措施。对工人的随访及其定期体检奠定了基础，建立了一个有可能用于放射流行病学研究的人群。当前的初步研究的目的是分析HMP SMCC工人的剂量形成因素。为此，使用“ Agilent 7800 ICP-MS”质谱仪测量了从在8个HMP车间雇用的54名工人收集的生物测定样品。三年后，对四名尿液中铀含量最高的工人进行了重复测量。特定位置剂量率测量的结果，HMP SMCC辐射与毒性安全服务的档案中提取了的长寿命α-颗粒活性浓度和等效平衡体积活性，并进行了分析，以全面评估这些工作场所的辐射状况。在提取车间和机械维修店测量了工人的最大尿铀浓度（分别高达26.7 µg / L和14.6 µg / L）。在其他场所工作的工人中的铀铀（占样本的约72％）主要处于自然条件下（<0.4 µg / L）可能出现的值范围内。发现尿液样本中铀浓度的个体差异很大（CV的60％至200％）。发现累积有效剂量对工作经验的线性依赖关系，每年的斜率为7.5 mSv。该坡度不取决于工作地点。对于被调查的工人，发现其累计有效剂量在低剂量（<100 mSv）和中等剂量（100-500 mSv）范围内。结论是，新组建的HMP SMCC工人具有改善中低剂量电离辐射对健康影响的知识的潜力。