Background and Aim:

Mild cognitive impairment (MCI) and dementia prevalence are expected to increase with aging. The DemTect is a very quick and easy tool to administer and recognize the early stages of dementia and MCI. In this study we aimed to evaluate the reliability and validity of a Turkish version of the DemTect and define cut off values for different age and educational levels. One of our aims is also to compare the sensitivity and specifity of the DemTect to other common screening tools.

Patients and Methods:

Fifty-four patients with MCI, 55 patients with dementia and 91 patients with subjective memory complaints (SMC) were enrolled in the study. The DemTect was translated into Turkish by forward-backward translation and compared with the Mini Mental State Examination (MMSE), the Quick Mild Cognitive Impairment Turkish version (QMCI-TR) and the Montreal Cognitive Assessment (MoCA). In order to test interrater reliability, the DemTect was administered to 11 patients, on the same day, by 2 trained raters. To establish test–retest reliability, the same rater scored the tool a second time on 11 patients within 2 weeks.

Results:

The median age of the patients was 73 (min-max: 65–90) years, 54.5% were female. We found a strong correlation between DemTect scores and the MMSE, the QMCI, and the MoCA (r = 0.725, r = 0.816, r = 0.821, respectively; p < 0.001). In ROC analysis, the cut-off point of the DemTect to differentiate MCI from SMC was 11.5 with 92.6% sensitivity, 91.2% specificity, AUC 0.973 and the cut-off point of the DemTect to differentiate dementia from SMC was 9.5 with 96.4% sensitivity, 100% specificity, AUC 0.916. Cronbach α was 0.823. Intraclass correlation coefficient was 0.873 (95% CI: 0.598–0.964) for interrater reliability and 0.966 (95% 0.777–0.982) for test-retest reliability (Cronbach α = 0.932, 0.966 respectively).

Conclusion:

The DemTect is a very reliable tool to assess Turkish patients with MCI and dementia.

中文翻译：

---

评估 MCI 和痴呆症的可靠工具：DemTect 针对土耳其人群的验证研究。

 背景和目标：

轻度认知障碍（MCI）和痴呆症的患病率预计会随着年龄的增长而增加。 DemTect 是一种非常快速且简单的工具，用于管理和识别痴呆症和 MCI 的早期阶段。在本研究中，我们旨在评估土耳其版本 DemTect 的可靠性和有效性，并定义不同年龄和教育水平的截止值。我们的目标之一是将 DemTect 与其他常见筛查工具的敏感性和特异性进行比较。

 患者和方法：

54 名 MCI 患者、55 名痴呆患者和 91 名主观记忆障碍 (SMC) 患者参与了这项研究。 DemTect 通过向前向后翻译的方式翻译成土耳其语，并与简易精神状态检查 (MMSE)、快速轻度认知障碍土耳其语版本 (QMCI-TR) 和蒙特利尔认知评估 (MoCA) 进行比较。为了测试评估者之间的可靠性，同一天，由 2 名训练有素的评估者对 11 名患者进行了 DemTect。为了确定重测可靠性，同一位评估者在 2 周内对 11 名患者再次对该工具进行了评分。

 结果：

患者的中位年龄为 73 岁（最小-最大：65-90）岁，其中 54.5% 为女性。我们发现 DemTect 分数与 MMSE、QMCI 和 MoCA 之间存在很强的相关性（分别为 r = 0.725、r = 0.816、r = 0.821；p < 0.001）。在 ROC 分析中，DemTect 区分 MCI 和 SMC 的分界点为 11.5，敏感性为 92.6%，特异性为 91.2%，AUC 0.973，DemTect 区分痴呆和 SMC 的分界点为 9.5，敏感性为 96.4% ，100% 特异性，AUC 0.916。克隆巴赫α值为0.823。组间相关系数为 0.873 (95% CI: 0.598–0.964)，测试者间信度为 0.873 (95% CI: 0.598–0.964)，重测信度为 0.966 (95% 0.777–0.982)（Cronbach α 分别为 0.932、0.966）。

 结论：

DemTect 是评估土耳其 MCI 和痴呆症患者的非常可靠的工具。