The association between chronic obstructive pulmonary disease (COPD) and occupational exposures are less studied in Bangladeshi context, despite the fact that occupational exposures are serious public health concerns in Bangladesh. Therefore, this study aimed to evaluate this association considering demographic, health and smoking characteristics of Bangladeshi population. This was a hospital-based quantitative study including 373 participants who were assessed for COPD through spirometry testing. Assessment of occupational exposures was based on both self-reporting by respondents and ALOHA based job exposure matrix (JEM). Here, among the self-reported exposed group (n = 189), 104 participants (55%) were found with COPD compared to 23 participants (12.5%) in unexposed group (n = 184) that differed significantly (p = 0.00). Similarly, among the JEM measured low (n = 103) and high exposed group (n = 236), 23.3% and 41.5% of the participants were found with COPD respectively; compared to unexposed group (14.7%; n = 34), that differed significantly also (p = 0.00). Likewise, participants with longer self-reported occupational exposures (>8 years) showed significantly (p = 0.00) higher proportions of COPD (79.5%) compared to 40.4% in shorter exposure group (1–8 years). Similarly, significant (p = 0.00) higher cases of COPD were observed among the longer cumulative exposure years (>9 years) group than the shorter cumulative exposure years (1–9 years) group in JEM. While combining smoking and occupational exposure, the chance of developing COPD among the current, former and non-smokers of exposed group were 7.4, 7.2 and 12.7 times higher respectively than unexposed group. Furthermore, logistic analysis revealed that after adjustments for confounding risk factors, the chance of developing COPD among the self-reported exposure group was 6.3 times higher (ORs: 6.3, p = 0.00) than unexposed group; and JEM exposure group has odds of 2.8 and 1.1 respectively (p<0.05) for high and low exposures. Further studies are needed to reinforce this association between COPD and occupational exposure in Bangladesh.

尽管在孟加拉国，慢性阻塞性肺疾病（COPD）与职业暴露之间的关联研究较少，尽管在孟加拉国职业暴露是严重的公共卫生问题。因此，本研究旨在评估考虑孟加拉人口的人口统计学，健康状况和吸烟特征的这种关联。这是一项基于医院的定量研究，其中包括373名通过肺活量测定法评估为COPD的参与者。职业暴露的评估是基于受访者的自我报告和基于ALOHA的工作暴露矩阵（JEM）。在这里，自我报告的暴露组（n = 189）中，有104名参与者（55％）被发现患有COPD，而未暴露组（n = 184）中有23名参与者（12.5％）存在显着差异（p = 0.00）。同样，在测量为低（n = 103）和高暴露组（n = 236）的JEM中，分别有23.3％和41.5％的参与者患有COPD；与未暴露组（14.7％； n = 34）相比，差异也很大（p = 0.00）。同样，自我报告职业暴露时间较长（> 8年）的受试者，COPD比例（79.5％）显着较高（p = 0.00），而短期暴露组（1-8年）则为40.4％。同样，在JEM中，较长的累积暴露年限（> 9年）组中观察到的COPD病例显着（p = 0.00）高，而较短的累积暴露年限（1–9年）组更高。在将吸烟与职业暴露相结合的情况下，暴露组当前，以前和非吸烟者发生COPD的机会分别比未暴露组高7.4倍，7.2倍和12.7倍。此外，逻辑分析显示，在对混杂风险因素进行调整后，自我报告的接触组发生COPD的机会比未接触组高6.3倍（OR：6.3，p = 0.00）。JEM暴露组的高和低暴露几率分别为2.8和1.1（p <0.05）。需要进一步研究以加强COPD与孟加拉国职业接触之间的联系。