Introduction

Inhalation injuries carry significant acute care burden including prolonged ventilator days and length of stay. However, few studies have examined post-acute outcomes of inhalation injury survivors. This study compares the long-term outcomes of burn survivors with and without inhalation injury.

Methods

Data collected by the Burn Model System National Database from 1993 to 2019 were analyzed. Demographic and clinical characteristics for adult burn survivors with and without inhalation injury were examined. Outcomes included employment status, Short Form-12/Veterans Rand-12 Physical Composite Score (SF-12/VR-12 PCS), Short Form-12/Veterans Rand-12 Mental Composite Score (SF-12/VR-12 MCS), and Satisfaction With Life Scale (SWLS) at 24 months post-injury. Regression models were used to assess the impacts of sociodemographic and clinical covariates on long-term outcome measures. All models controlled for demographic and clinical characteristics.

Results

Data from 1,871 individuals were analyzed (208 with inhalation injury; 1,663 without inhalation injury). The inhalation injury population had a median age of 40.1 years, 68.8% were male, and 69% were White, non-Hispanic. Individuals that sustained an inhalation injury had larger burn size, more operations, and longer lengths of hospital stay (p<0.001). Individuals with inhalation injury were less likely to be employed at 24 months post-injury compared to survivors without inhalation injury (OR = 0.63, p = 0.028). There were no significant differences in PCS, MCS, or SWLS scores between groups in adjusted regression analyses.

Conclusions

Burn survivors with inhalation injury were significantly less likely to be employed at 24 months post-injury compared to survivors without inhalation injury. However, other health-related quality of life outcomes were similar between groups. This study suggests distinct long-term outcomes in adult burn survivors with inhalation injury which may inform future resource allocation and treatment paradigms.

中文翻译：

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吸入损伤与烧伤人群的长期就业相关：从烧伤模型系统国家数据库的横断面检查中获得的结果。

介绍

吸入伤害会带来严重的急性护理负担，包括呼吸机天数的延长和住院时间的延长。但是，很少有研究检查吸入性损伤幸存者的急性后结局。这项研究比较了有或没有吸入损伤的烧伤幸存者的长期结果。

方法

分析了Burn模型系统国家数据库从1993年到2019年收集的数据。检查了有和没有吸入损伤的成年烧伤幸存者的人口统计学和临床​​特征。结果包括就业状况，12年级/退伍军人12短小身体综合得分（SF-12 / VR-12 PCS），12年级/退伍军人12短小心理综合得分（SF-12 / VR-12 MCS）以及受伤后24个月的生活满意度量表（SWLS）。回归模型用于评估社会人口统计学和临床​​协变量对长期预后指标的影响。所有模型均根据人口统计和临床特征进行控制。

结果

分析了来自1,871个人的数据（208例有吸入损伤； 1,663例没有吸入损伤）。吸入损伤人群的中位年龄为40.1岁，男性为68.8％，非西班牙裔为白人，为69％。遭受吸入性伤害的个体的烧伤面积更大，手术次数更多，住院时间更长（p <0.001）。与没有吸入损伤的幸存者相比，吸入损伤的个体在受伤后24个月受雇的可能性较小（OR = 0.63，p = 0.028）。在调整后的回归分析中，各组之间的PCS，MCS或SWLS评分没有显着差异。

结论

与没有吸入损伤的幸存者相比，有吸入损伤的烧伤幸存者在受伤后24个月受雇的可能性大大降低。但是，其他与健康相关的生活质量结果在各组之间相似。这项研究表明，吸入性损伤的成年烧伤幸存者具有长期不同的结局，这可能为将来的资源分配和治疗方法提供依据。